C-JUN N-TERMINAL KINASE
- Product Name
- C-JUN N-TERMINAL KINASE
- Chemical Name
- C-JUN N-TERMINAL KINASE
- Synonyms
- JNK3;JNK3A;MAPK10;PRKM10;SAPK1b;p493F12;FLJ12099;FLJ33785;MGC50974;p54bSAPK
- CBNumber
- CB7769250
- Formula Weight
- 0
- MOL File
- Mol file
C-JUN N-TERMINAL KINASE Property
- storage temp.
- −70°C
- form
- buffered aqueous glycerol solution
- biological source
- mouse
Safety
- Safety Statements
- 23-24/25
- WGK Germany
- 1
N-Bromosuccinimide Price
- Product number
- SAB1412174
- Product name
- ANTI-MAPK10 antibody produced in mouse
- Purity
- clone 3A3-1A8, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $541
- Updated
- 2025/07/31
- Product number
- orb529641
- Product name
- MAPK10
- Packaging
- 10μg
- Price
- $579.7
- Updated
- 2021/12/16
- Product number
- orb596871
- Product name
- MAPK10
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
- Product number
- PRO0004497
- Product name
- JNK3
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.91
- Updated
- 2021/12/16
C-JUN N-TERMINAL KINASE Chemical Properties,Usage,Production
Uses
JNK-3 is an inhibitor of JNK kinase which may be used in the treatment of many hyperactive JNK signaling diseases such as cancer, inflammatory diseases and neurodegenerative diseases.
General Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)
C-JUN N-TERMINAL KINASE Preparation Products And Raw materials
Raw materials
Preparation Products
C-JUN N-TERMINAL KINASE Suppliers
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- United States
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- United States
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