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PYRILAMINE

Product Name
PYRILAMINE
CAS No.
91-84-9
Chemical Name
PYRILAMINE
Synonyms
Pyra;Dipane;Histan;Isamin;Parmal;rd2786;rp2786;Nisaval;Coradon;Enrumay
CBNumber
CB7775947
Molecular Formula
C17H23N3O
Formula Weight
285.38
MOL File
91-84-9.mol
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PYRILAMINE Property

Melting point:
131-132 °C
Boiling point:
bp5 201°; bp0.06 168-172°
Density 
1.0141 (rough estimate)
refractive index 
nD25 1.5760-1.5765
pka
pKa 4.02(H2O t=25 c=0.002 to 0.01) (Uncertain);8.92 (Uncertain)
Water Solubility 
3.425g/L(37.5 ºC)
EPA Substance Registry System
Mepyramine (91-84-9)
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Safety

Hazardous Substances Data
91-84-9(Hazardous Substances Data)
Toxicity
LD50 orally in mice: 312 mg/kg (Schlichtergroll)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S347108
Product name
N,N-DIMETHYL-N''-(4-METHOXYBENZYL)-N''-(2-PYRIDYL)ETHYLENEDIAMINE
Purity
AldrichCPR
Packaging
250MG
Price
$179
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0006944
Product name
PYRILAMINE
Purity
95.00%
Packaging
5MG
Price
$501.61
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0006944
Product name
PYRILAMINE
Purity
95.00%
Packaging
1G
Price
$1529.85
Updated
2021/12/16
Crysdot
Product number
CD11015848
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine
Purity
95+%
Packaging
5g
Price
$2213
Updated
2021/12/16
Crysdot
Product number
CD11015848
Product name
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine
Purity
95+%
Packaging
1g
Price
$837
Updated
2021/12/16
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PYRILAMINE Chemical Properties,Usage,Production

Uses

Antihistaminic.

Uses

Pyrilamine is also used for allergy symptoms and rhinitis.

Uses

N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain.

Definition

ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

brand name

Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel).

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037

General Description

Viscous brown liquid.

Air & Water Reactions

May be sensitive to light. Insoluble in water.

Reactivity Profile

PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.

Health Hazard

SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia.

Fire Hazard

Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible.

PYRILAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRILAMINE Suppliers

Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18043
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9649
Advantage
58
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15951
Advantage
58
Chengdu Saint - Kay Biotechnology Co., Ltd.
Tel
028-85157043 15882256948
Email
676046971@qq.com
Country
China
ProdList
4390
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Finetech Industry Limited
Tel
+86-27-87465837 +8618971612321
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9640
Advantage
58
Xi'an ZB Biotech Co.,Ltd
Tel
Email
sales03@xazbbio.com
Country
CHINA
ProdList
719
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15357
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-89586680 +86-18192503167
Fax
+86-29-88380327
Email
1026@dideu.com
Country
China
ProdList
7724
Advantage
58

91-84-9, PYRILAMINERelated Search:


  • 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-
  • 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl-
  • 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin
  • Pyrilamine (base and/or unspecified salts)
  • MEPYRAMINE(PYRILAMINE)
  • 2-dimethylaminoethyl-(4-methoxybenzyl)-(2-pyridyl)amine
  • N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine
  • N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
  • N-(4-Methoxy-benzyl)-N,N-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine
  • MEPYRAMINE BASE
  • Nisaval
  • Triaminic
  • 2-((2-(dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine
  • 2-((2-dimethylaminoethyl)(p-methoxybenzyl)amino)pyridine
  • 2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine
  • 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine
  • Afko-Hist
  • Anhistabs
  • Anhistol
  • Antalergan
  • Antallergan
  • Antamine
  • Anthisan
  • Copsamine
  • Coradon
  • Dipane
  • Dorantamin
  • Enrumay
  • Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-
  • Harvamine
  • Histacap
  • Histalon
  • Histan
  • Histapyran
  • Histasan
  • Isamin
  • Kriptin
  • Maranhist
  • Mepiramine
  • Mepyramin
  • Mepyramine
  • Mepyren
  • n-(para-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine
  • N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine
  • N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine
  • N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine
  • n-(p-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine
  • N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(alpha-pyridyl)-ethylenediaminene
  • N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2 -Pyridyl)ethylenediamine
  • N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine
  • n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-1,2-ethanediamine
  • NCI-C60651
  • N-Dimethylamino-aethyl-N-p-methoxy-benzyl-alpha-amino-pyridin-maleat
  • Neoantergan
  • Neo-Bridal
  • n-para-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine
  • n-p-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine
  • Nyscaps