PYRILAMINE

Product Name: PYRILAMINE
CAS No.: 91-84-9
Chemical Name: PYRILAMINE
Synonyms: Pyra;Dipane;Histan;Isamin;Parmal;rd2786;rp2786;Nisaval;Coradon;Enrumay
CBNumber: CB7775947
Molecular Formula: C17H23N3O
Formula Weight: 285.38
MOL File: 91-84-9.mol

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PYRILAMINE Property

Melting point:: 131-132 °C
Boiling point:: bp5 201°; bp0.06 168-172°
Density: 1.0141 (rough estimate)
refractive index: nD25 1.5760-1.5765
pka: pKa 4.02(H2O t=25 c=0.002 to 0.01) (Uncertain);8.92 (Uncertain)
Water Solubility: 3.425g/L(37.5 ºC)
EPA Substance Registry System: Mepyramine (91-84-9)

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Safety

Hazardous Substances Data: 91-84-9(Hazardous Substances Data)
Toxicity: LD50 orally in mice: 312 mg/kg (Schlichtergroll)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S347108
Product name: N,N-DIMETHYL-N''-(4-METHOXYBENZYL)-N''-(2-PYRIDYL)ETHYLENEDIAMINE
Purity: AldrichCPR
Packaging: 250MG
Price: $179
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: API0006944
Product name: PYRILAMINE
Purity: 95.00%
Packaging: 5MG
Price: $501.61
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006944
Product name: PYRILAMINE
Purity: 95.00%
Packaging: 1G
Price: $1529.85
Updated: 2021/12/16

Crysdot

Product number: CD11015848
Product name: N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine
Purity: 95+%
Packaging: 5g
Price: $2213
Updated: 2021/12/16

Crysdot

Product number: CD11015848
Product name: N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine
Purity: 95+%
Packaging: 1g
Price: $837
Updated: 2021/12/16

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PYRILAMINE Chemical Properties,Usage,Production

Uses

Antihistaminic.

Uses

Pyrilamine is also used for allergy symptoms and rhinitis.

Uses

N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain.

Definition

ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

brand name

Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel).

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037

General Description

Viscous brown liquid.

Air & Water Reactions

May be sensitive to light. Insoluble in water.

Reactivity Profile

PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.

Health Hazard

SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia.

Fire Hazard

Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible.

PYRILAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRILAMINE Suppliers

China 15 Germany 1 India 2 Slovakia 1 South Korea 1 United Kingdom 2 United States 8 Global 30

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18042
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Aikon International Limited

Tel: 025-58851090 13611564524
Fax: (6)02557626880
Email: lwan@aikonchem.com
Country: China
ProdList: 15951
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4391
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Finetech Industry Limited

Tel: +86-27-87465837 +8618971612321
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9639
Advantage: 58

Xi'an ZB Biotech Co.,Ltd

Tel
Email: sales03@xazbbio.com
Country: CHINA
ProdList: 719
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15354
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
Advantage: 58

91-84-9, PYRILAMINERelated Search:

Pyrilamine/Brompheniramine Pyrilamine(Mepyramine)Maleate pyrilamine N-oxide Pyrilamine base/maleate N'-(4-CYANOBUTYL)-N-(4-METHOXYBENZYL)-N'-METHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE PYRILAMINE MALEATE,PYRILAMINE MALEATE SALT,PYRILAMINE MALEATE USP/NF,PYRILAMINE MALEATE METHANOL SOLUTION N-(4-methoxybenzyl-N',N'-dimethyl-N-2-pyridylethylenediamine monohydrochloride PYRILAMINE, [PYRIDINYL 5-3H]-,[PYRIDINYL-5-3H]PYRILAMINE PYRILAMINE TANNATE PYRILAMINE N'-(5-AMINOPENTYL)-N-(4-METHOXYBENZYL)-N'-METHYL-N-2-PYRIDINYL-1,2-ETHANEDIAMINE, DIMALEATE SALT

1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-

1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl-

2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin

Pyrilamine (base and/or unspecified salts)

MEPYRAMINE(PYRILAMINE)

2-dimethylaminoethyl-(4-methoxybenzyl)-(2-pyridyl)amine

N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine

N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine

N-(4-Methoxy-benzyl)-N,N-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine

MEPYRAMINE BASE

Nisaval

Triaminic

2-((2-(dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine

2-((2-dimethylaminoethyl)(p-methoxybenzyl)amino)pyridine

2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine

2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine

Afko-Hist

Anhistabs

Anhistol

Antalergan

Antallergan

Antamine

Anthisan

Copsamine

Coradon

Dipane

Dorantamin

Enrumay

Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)-

Harvamine

Histacap

Histalon

Histan

Histapyran

Histasan

Isamin

Kriptin

Maranhist

Mepiramine

Mepyramin

Mepyramine

Mepyren

n-(para-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine

N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine

N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine

N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine

n-(p-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine

N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(alpha-pyridyl)-ethylenediaminene

N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2 -Pyridyl)ethylenediamine

N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine

n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-1,2-ethanediamine

NCI-C60651

N-Dimethylamino-aethyl-N-p-methoxy-benzyl-alpha-amino-pyridin-maleat

Neoantergan

Neo-Bridal

n-para-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine

n-p-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine

Nyscaps