ChemicalBook > CAS DataBase List > L-NIO DIHYDROCHLORIDE

L-NIO DIHYDROCHLORIDE

Product Name
L-NIO DIHYDROCHLORIDE
CAS No.
36889-13-1
Chemical Name
L-NIO DIHYDROCHLORIDE
Synonyms
L-NIO;L-NIO, 2HCL;L-NIO dihydrochlorid;L-NIO DIHYDROCHLORIDE;L-NIO (hydrochloride);n(g)-iminoethylornithine;L-N5-(1-Iminoethyl)ornithine;L-Ornithine, N5-(1-iminoethyl)-;L-NIO DIHYDROCHLORIDE USP/EP/BP;L-N5-(1-Iminoethyl)Ornithine,HCl
CBNumber
CB7776636
Molecular Formula
C7H15N3O2
Formula Weight
173.21
MOL File
36889-13-1.mol
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L-NIO DIHYDROCHLORIDE Property

Melting point:
225-226°C
storage temp. 
-20°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety

Safety Statements 
24/25
HS Code 
29224985
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
80320
Product name
L-NIO (hydrochloride)
Purity
≥95%
Packaging
5mg
Price
$17
Updated
2024/03/01
Cayman Chemical
Product number
80320
Product name
L-NIO (hydrochloride)
Purity
≥95%
Packaging
10mg
Price
$30
Updated
2024/03/01
Cayman Chemical
Product number
80320
Product name
L-NIO (hydrochloride)
Purity
≥95%
Packaging
50mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
80320
Product name
L-NIO (hydrochloride)
Purity
≥95%
Packaging
100mg
Price
$207
Updated
2024/03/01
Tocris
Product number
0546
Product name
L-NIOdihydrochloride
Packaging
10
Price
$86
Updated
2021/12/16
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L-NIO DIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

L-NIO is a non-selective inhibitor of all NOS isoforms. The Ki values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-NIO inhibits endothelial-dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin.

Chemical Properties

White Crystalline Solid

Uses

A potent and reversible inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells

Definition

ChEBI: L-NIO is a L-alpha-amino acid.

Biological Activity

Potent inhibitor of endothelial NO synthase (IC 50 = 500 nM). Also inhibits iNOS and nNOS. Active in vivo .

L-NIO DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-NIO DIHYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
10007
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
22883
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58

36889-13-1, L-NIO DIHYDROCHLORIDERelated Search:


  • L-NIO
  • L-NIO, 2HCL
  • n(g)-iminoethylornithine
  • NG-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE
  • N5-(1-IMINOETHYL)-L-ORNITHINE DIHYDROCHLORIDE
  • N(5)-(1-IMINOETHYL)-L-ORNITHINE HCL
  • N5-(1-IMINOETHYL)-L-ORNITHINE HYDROCHLORIDE
  • L-N5-(I-IMINOETHYL)ORNITHINE HYDROCHLORI DE POTENT IRREVERSIBLE N
  • L-N5-(1-Iminoethyl)Ornithine,HCl
  • L-NIO DIHYDROCHLORIDE
  • L-N5-(1-IMINOETHYL)-ORNITHINE 2HCL
  • L-N5-(1-IMINOETHYL)ORNITHINE, DIHYDROCHLORIDE
  • L-N5-(1-IMINOETHYL) ORNITHINE, HYDROCHLORIDE
  • L-N5-(I-IMINOETHYL)ORNITHINE HYDROCHLORIDE
  • L-NIO (hydrochloride)
  • L-N5-(1-Iminoethyl)ornithine
  • L-N5-(1-Iminoethyl)-ornithine dihydrochloride,97%
  • L-Ornithine, N5-(1-iminoethyl)-
  • L-NIOdihydrochloride,N5-(1-Iminoethyl)-L-ornithinedihydrochloride
  • L-NIO DIHYDROCHLORIDE USP/EP/BP
  • L-NIO dihydrochlorid
  • 36889-13-1
  • C7H15N3O2HCl
  • C7H16ClN3O2
  • C7H15N3O22HCl
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Nitric Oxide Reagents
  • Nitric Oxide