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SQUALESTATIN

Product Name
SQUALESTATIN
CAS No.
144541-82-2
Chemical Name
SQUALESTATIN
Synonyms
L-694,599;SQUALESTATIN;ZARAGOZIC ACID A SODIUM SALT;Zaragozic acid A trisodium salt
CBNumber
CB7779233
Molecular Formula
C35H47NaO14
Formula Weight
714.74
MOL File
Mol file
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SQUALESTATIN Property

storage temp. 
-20°C
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Z2626
Product name
Zaragozic acid A trisodium salt
Purity
≥95% (HPLC), microbial
Packaging
5mg
Price
$624
Updated
2024/03/01
TRC
Product number
Z150603
Product name
Zaragozic acid A trisodium salt
Packaging
1mg
Price
$470
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001014
Product name
ZARAGOZIC ACID A TRISODIUM SALT
Purity
95.00%
Packaging
5MG
Price
$1036.09
Updated
2021/12/16
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SQUALESTATIN Chemical Properties,Usage,Production

Uses

Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.

Uses

Zaragozic acid A trisodium salt has been used as:

  • a component of serum-free medium for human embryonic kidney cells in a wound scratch assay to test its effect on wound healing
  • a farnesyl-diphosphate farnesyltransferase 1 (FDFT1) or squalene synthase inhibitor in stromal cells
  • a cholesterol synthesis inhibitor in T cells

Biochem/physiol Actions

Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.

SQUALESTATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SQUALESTATIN Suppliers

Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24990
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
Advantage
58

144541-82-2, SQUALESTATINRelated Search:


  • SQUALESTATIN
  • L-694,599
  • Zaragozic acid A trisodium salt
  • ZARAGOZIC ACID A SODIUM SALT
  • 144541-82-2