ChemicalBook > CAS DataBase List > SQUALESTATIN
SQUALESTATIN
- Product Name
- SQUALESTATIN
- CAS No.
- 144541-82-2
- Chemical Name
- SQUALESTATIN
- Synonyms
- L-694,599;SQUALESTATIN;ZARAGOZIC ACID A SODIUM SALT;Zaragozic acid A trisodium salt
- CBNumber
- CB7779233
- Molecular Formula
- C35H47NaO14
- Formula Weight
- 714.74
- MOL File
- Mol file
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SQUALESTATIN Property
- storage temp.
- -20°C
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- Z2626
- Product name
- Zaragozic acid A trisodium salt
- Purity
- ≥95% (HPLC), microbial
- Packaging
- 5mg
- Price
- $624
- Updated
- 2024/03/01
TRC
- Product number
- Z150603
- Product name
- Zaragozic acid A trisodium salt
- Packaging
- 1mg
- Price
- $470
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0001014
- Product name
- ZARAGOZIC ACID A TRISODIUM SALT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $1036.09
- Updated
- 2021/12/16
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SQUALESTATIN Chemical Properties,Usage,Production
Uses
Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.
Uses
Zaragozic acid A trisodium salt has been used as:
- a component of serum-free medium for human embryonic kidney cells in a wound scratch assay to test its effect on wound healing
- a farnesyl-diphosphate farnesyltransferase 1 (FDFT1) or squalene synthase inhibitor in stromal cells
- a cholesterol synthesis inhibitor in T cells
Biochem/physiol Actions
Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.
SQUALESTATIN Preparation Products And Raw materials
Raw materials
Preparation Products
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SQUALESTATIN Suppliers
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- 020-39119399 18927568969
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- China
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- China
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- +1-+1(833)-552-7181
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- Country
- United States
- ProdList
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