4-(Trifluoromethyl)phenacyl bromide

Product Name: 4-(Trifluoromethyl)phenacyl bromide
CAS No.: 383-53-9
Chemical Name: 4-(Trifluoromethyl)phenacyl bromide
Synonyms: 2-BroMo-4&priMe;BUTTPARK 35\01-55;methyl 3-cyano-5-nitrobenzoate;4-TRIFLUOROMETHYLPHENACYL BROMIDE;4-(Trifluoromethyl)phecyl bromide;4'-(TRIFLUOROMETHYL)PHENACYL BROMIDE;4-(Trifluoromethyl)phenacylbromide97%;4-(Trifluoromethyl)phenacyl bromide 97%;2-Bromo-4'-(trifluoromethyl)acetophenon;2-Bromo-4'-(trifluoromethyl)acetophenone
CBNumber: CB7782499
Molecular Formula: C9H6BrF3O
Formula Weight: 267.04
MOL File: 383-53-9.mol

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4-(Trifluoromethyl)phenacyl bromide Property

Melting point:: 45 °C
Boiling point:: 264.2±40.0 °C(Predicted)
Density: 1.592±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: soluble in Methanol
form: powder to crystal
color: White to Yellow to Orange
InChI: 1S/C9H6BrF3O/c10-5-8(14)6-1-3-7(4-2-6)9(11,12)13/h1-4H,5H2
InChIKey: HEMROKPXTCOASZ-UHFFFAOYSA-N
SMILES: FC(F)(F)c1ccc(cc1)C(=O)CBr
CAS DataBase Reference: 383-53-9(CAS DataBase Reference)

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Safety

Hazard Codes: C,Xi
Risk Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45-36
RIDADR: 1759
WGK Germany: 3
HazardClass: CORROSIVE
PackingGroup: III
HS Code: 29147000
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 669466
Product name: 2-Bromo-4′-(trifluoromethyl)acetophenone
Purity: 95%
Packaging: 1g
Price: $26.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 669466
Product name: 2-Bromo-4′-(trifluoromethyl)acetophenone
Purity: 95%
Packaging: 5g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: T2747
Product name: 2-Bromo-4'-(trifluoromethyl)acetophenone
Purity: >95.0%(GC)
Packaging: 5g
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: T2747
Product name: 2-Bromo-4'-(trifluoromethyl)acetophenone
Purity: >95.0%(GC)
Packaging: 25g
Price: $293
Updated: 2025/07/31

TRC

Product number: B415118
Product name: 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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4-(Trifluoromethyl)phenacyl bromide Chemical Properties,Usage,Production

Chemical Properties

White powder or crystal

Synthesis

313343-88-3

383-53-9

General procedure for the synthesis of 2-bromo-4'-(trifluoromethyl)acetophenone using 1-(bromoethynyl)-4-(trifluoromethyl)benzene as starting material: a mixed solution of haloalkynes (0.5 mmol), silver fluoride (5 mol%), and water (1 eq.) in trifluoroacetic acid (1 mL) was stirred for 6 hours at 40 °C. Upon completion of the reaction, the trifluoroacetic acid was recovered by distillation for reuse. The residue was purified by column chromatographic separation to afford the target product 2-bromo-4'-(trifluoromethyl)acetophenone.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 7, p. 1373 - 1375
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 1, p. 116 - 121
[3] Tetrahedron, 2016, vol. 72, # 27-28, p. 3818 - 3822
[4] Tetrahedron Letters, 2016, vol. 57, # 45, p. 4983 - 4986
[5] Chinese Journal of Chemistry, 2016, vol. 34, # 12, p. 1251 - 1254

4-(Trifluoromethyl)phenacyl bromide Preparation Products And Raw materials

Raw materials

1,4-Dioxane Diethyl ether Bromine

Preparation Products

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4-(Trifluoromethyl)phenacyl bromide Suppliers

Belgium 1 China 102 France 1 Germany 3 India 4 Italy 1 Japan 1 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 10 United States 18 Global 144

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View Lastest Price from 4-(Trifluoromethyl)phenacyl bromide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-(Trifluoromethyl)phenacyl bromide 383-53-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-31

Honest Joy Holdings Limited

Product: 4-(Trifluoromethyl)phenacyl bromide 383-53-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.7%
Supply Ability: 100 tons
Release date: 2022-02-21

Career Henan Chemical Co

Product: 4-(Trifluoromethyl)phenacyl bromide 383-53-9
Price: US $1.00/KG
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2019-12-20

383-53-9, 4-(Trifluoromethyl)phenacyl bromideRelated Search:

4'-(Trifluoromethyl)acetophenone 2-FLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE 2-BROMO-2',6'-DICHLORO-4'-(TRIFLUOROMETHYL)-ACETOPHENONE 4-(Trifluoromethyl)phenacyl bromide 2,3-DIFLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE 2,4-BIS(TRIFLUOROMETHYL)PHENACYL BROMIDE ETHYL 2-BROMO-3-(4-TRIFLUOROMETHYLPHENYL)-3-OXO-PROPANOATE 3-FLUORO-4-(TRIFLUOROMETHYL)PHENACYL BROMIDE 2-BROMO-1-(4-TRIFLUOROMETHYL-PHENYL)-PENTAN-1-ONE

2-broMo-1-(4-(trifluoroMethyl)phenyl)ethanone

BUTTPARK 35\01-55

2-Bromo-4'-(trifluoromethyl)acetophenone, 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one

4'-(TRIFLUOROMETHYL)PHENACYL BROMIDE

4-TRIFLUOROMETHYLPHENACYL BROMIDE

2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]-1-ETHANONE

2-BROMO-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHAN-1-ONE

2-Bromo-1-[4-(trifluoromethyl)phenyl]ethan-1-one, tech

4-(Trifluoromethyl)phenacyl bromide 97%

4-(Trifluoromethyl)phenacylbromide97%

4-(TRIFLUOROMETHYL)PHENACYL BROMIDE: TECH.

2-Bromo-4'-(trifluoromethyl)acetophenon

methyl 3-cyano-5-nitrobenzoate

2-BroMo-4&priMe

4-(Trifluoromethyl)phecyl bromide

Ethanone, 2-bromo-1-[4-(trifluoromethyl)phenyl]-

2-Bromo-4'-(trifluoromethyl)acetophenone

2-Bromo-4′-(trifluoromethyl)acetophenone, CAS 383-53-9

383-53-9

C9H6BrF3O

Building Blocks

Carbonyl Compounds

C9

Ketones

Organic Building Blocks

Benzene series