2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE
- Product Name
- 2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE
- CAS No.
- 50432-67-2
- Chemical Name
- 2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE
- Synonyms
- 2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE;3,4-Pyridinediamine, 2-chloro-N4-methyl-;2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE ISO 9001：2015 REACH
- CBNumber
- CB7795266
- Molecular Formula
- C6H8ClN3
- Formula Weight
- 157.6
- MOL File
- 50432-67-2.mol
2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Brown to dark brown Solid
N-Bromosuccinimide Price
- Product number
- C611198
- Product name
- 2-Chloro-N4-methylpyridine-3,4-diamine
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FC147667
- Product name
- 2-Chloro-n4-methylpyridine-3,4-diamine
- Packaging
- 250mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- FC147667
- Product name
- 2-Chloro-n4-methylpyridine-3,4-diamine
- Packaging
- 500mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 072557
- Product name
- 2-Chloro-N4-methylpyridine-3,4-diamine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $231
- Updated
- 2021/12/16
- Product number
- 072557
- Product name
- 2-Chloro-N4-methylpyridine-3,4-diamine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $500
- Updated
- 2021/12/16
2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE Chemical Properties,Usage,Production
Synthesis
1633-41-6
50432-67-2
General procedure for the synthesis of 2-chloro-N4-methylpyridine-3,4-diamine from 4-methylamino-3-nitropyridine: 0.61 g (4.0 mmol) of 4-methylamino-3-nitropyridine was dissolved in 3.5 mL of concentrated hydrochloric acid. The reaction mixture was heated to 90 °C. Subsequently, a suspension of 3.5 g (15 mmol) of stannous chloride in concentrated hydrochloric acid (4 mL) was slowly added. The reaction mixture was reacted under reflux conditions for 3 hours. Upon completion of the reaction, the suspension was cooled to room temperature, poured into 75 mL of water and extracted with dichloromethane (2 x 30 mL). The organic layers were combined, dried with magnesium sulfate and concentrated in vacuum to give 0.60 g (95% yield) of 2-chloro-N4-methylpyridine-3,4-diamine as a white solid with a melting point of 168-169 °C.
References
[1] Patent: WO2005/26164, 2005, A1. Location in patent: Page/Page column 42
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 22, p. 6887 - 6896
[3] Patent: EP1568699, 2005, A1. Location in patent: Page/Page column 82
2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE Suppliers
- Tel
- --
- Fax
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- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from 2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE manufacturers
- Product
- 2-CHLORO-N4-METHYLPYRIDINE-3,4-DIAMINE 50432-67-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-07