N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3

Product Name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
CAS No.: 2107273-62-9
Chemical Name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
Synonyms: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3;2-(3-(5-((2,5,8,11-Tetraoxatridecan-13-yl)oxy)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-5-((3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy)-1,3,3-trimethyl-3H-indol-1-ium chloride
CBNumber: CB78054774
Molecular Formula: C45H65ClN2O10
Formula Weight: 829.47
MOL File: 2107273-62-9.mol

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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 Property

solubility: Soluble in Water, DMSO, DMF, DCM

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23038
Product name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
Purity: 95%
Packaging: 1mg
Price: $230
Updated: 2021/12/16

BroadPharm

Product number: BP-23038
Product name: N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3
Purity: 95%
Packaging: 2mg
Price: $350
Updated: 2021/12/16

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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 Chemical Properties,Usage,Production

Description

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG linker containing cyanine dye with excitation/emmission maximum 555/570 nm and an alkyne group, which enables copper-catalyzed Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media.

Uses

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 Preparation Products And Raw materials

Raw materials

Preparation Products

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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 Suppliers

China 13 United States 2 Global 15

Zhengzhou Acme Chemical Co., Ltd.

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TargetMol Chemicals Inc.

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Henan Mengtai Pharmaceutical Technology Co., Ltd

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2107273-62-9, N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3Related Search:

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3

2-(3-(5-((2,5,8,11-Tetraoxatridecan-13-yl)oxy)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-5-((3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy)-1,3,3-trimethyl-3H-indol-1-ium chloride

2107273-62-9