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N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3

Product Name
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
CAS No.
2107273-64-1
Chemical Name
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
Synonyms
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
CBNumber
CB33363976
Molecular Formula
C44H66ClN5O10
Formula Weight
860.49
MOL File
2107273-64-1.mol
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 Property

solubility 
Soluble in Water, DMSO, DMF, DCM
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23039
Product name
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
Purity
98%
Packaging
1mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-23039
Product name
N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
Purity
98%
Packaging
2mg
Price
$350
Updated
2021/12/16
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 Chemical Properties,Usage,Production

Description

N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG linker containing cyanine dye with excitation/emmission maximum 555/570 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media.

Uses

N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 Preparation Products And Raw materials

Raw materials

Preparation Products

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N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 Suppliers

China 9 United States 3 Global 12
Jinan elephant international trading co., LTD
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2107273-64-1, N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3Related Search:

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