(2-AMINO-6-CHLORO-PHENYL)-METHANOL
- Product Name
- (2-AMINO-6-CHLORO-PHENYL)-METHANOL
- CAS No.
- 39885-08-0
- Chemical Name
- (2-AMINO-6-CHLORO-PHENYL)-METHANOL
- Synonyms
- 2-Chloro-6-aminobenzyl alcohol;2-Amino-6-chlorobenzyl alcohol;2-Amino-6-chlorobenzenemethanol;Benzenemethanol,2-amino-6-chloro-;(2-AMINO-6-CHLORO-PHENYL)-METHANOL
- CBNumber
- CB7843473
- Molecular Formula
- C7H8ClNO
- Formula Weight
- 157.6
- MOL File
- 39885-08-0.mol
(2-AMINO-6-CHLORO-PHENYL)-METHANOL Property
- Melting point:
- 76-78℃
- Boiling point:
- 324.2±27.0 °C(Predicted)
- Density
- 1.341±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- solid
- pka
- 13.84±0.10(Predicted)
- color
- White to off-white
Safety
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR931392
- Product name
- (2-Amino-6-chlorophenyl)methanol
- Purity
- 97%
- Packaging
- 5g
- Price
- $73
- Updated
- 2021/12/16
- Product number
- HCH0068986
- Product name
- (2-AMINO-6-CHLORO-PHENYL)-METHANOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.81
- Updated
- 2021/12/16
- Product number
- 5253AB
- Product name
- (2-Amino-6-chlorophenyl)methanol
- Packaging
- 1g
- Price
- $127
- Updated
- 2021/12/16
- Product number
- 5253AB
- Product name
- (2-Amino-6-chlorophenyl)methanol
- Packaging
- 5g
- Price
- $282
- Updated
- 2021/12/16
- Product number
- CM101484
- Product name
- Benzenemethanol,2-amino-6-chloro-
- Purity
- 95+%
- Packaging
- 5g
- Price
- $316
- Updated
- 2021/12/16
(2-AMINO-6-CHLORO-PHENYL)-METHANOL Chemical Properties,Usage,Production
Synthesis
2148-56-3
39885-08-0
General procedure for the synthesis of (2-amino-6-chlorophenyl)-methanol from 2-amino-6-chlorobenzoic acid: 50.0 g (286 mmol) of 2-amino-6-chlorobenzoic acid was dissolved in 300 mL of anhydrous tetrahydrofuran (THF). The resulting solution was cooled to 0-10°C, followed by the slow addition of 450 mL of 1.0 M lithium aluminum hydride in THF solution. The reaction mixture was gradually warmed to room temperature and stirred continuously at room temperature overnight. Upon completion of the reaction, 300 mL of 10% aqueous sodium hydroxide solution was carefully added to the mixture to quench the reaction. The organic phase was separated and washed sequentially with ethyl acetate and water. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent, yielding 42 g (270 mmol, 95% yield) of a yellow solid product, which could be used without further purification.
References
[1] Patent: CN107722059, 2018, A. Location in patent: Paragraph 0094; 0097; 0098; 0099
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 6, p. 2080 - 2092
[4] Patent: US2018/105527, 2018, A1. Location in patent: Paragraph 0783-0785
[5] Patent: WO2006/10142, 2006, A2. Location in patent: Page/Page column 70
(2-AMINO-6-CHLORO-PHENYL)-METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2-AMINO-6-CHLORO-PHENYL)-METHANOL manufacturers
- Product
- (2-AMINO-6-CHLORO-PHENYL)-METHANOL 39885-08-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-07-03