2-AMINO-4,6-DICHLOROBENZOIC ACID
Uses- Product Name
- 2-AMINO-4,6-DICHLOROBENZOIC ACID
- CAS No.
- 20776-63-0
- Chemical Name
- 2-AMINO-4,6-DICHLOROBENZOIC ACID
- Synonyms
- BUTTPARK 49\07-45;2-AMINO-4,6-DICHLOROBENZOIC ACID;Benzoic acid, 2-amino-4,6-dichloro-;2-AMINO-4,6-DICHLOROBENZOIC ACID FOR SYN;2-Amino-4,6-dichlorobenzoic acid for synthesis;2-AMINO-4,6-DICHLOROBENZOIC ACID ISO 9001：2015 REACH
- CBNumber
- CB2258159
- Molecular Formula
- C7H5Cl2NO2
- Formula Weight
- 206.03
- MOL File
- 20776-63-0.mol
2-AMINO-4,6-DICHLOROBENZOIC ACID Property
- Melting point:
- 178.0-178.5 °C (decomp)
- Boiling point:
- 375.2±42.0 °C(Predicted)
- Density
- 1.607±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- 1.25g/l
- pka
- 3.42±0.25(Predicted)
- form
- solid
- Appearance
- Light yellow to light brown Solid
- PH
- 2.3 (H2O, 20℃)
- Water Solubility
- 1.25g/L
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 8.15106
- Product name
- 2-Amino-4,6-dichlorobenzoic acid
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $605
- Updated
- 2025/07/31
- Product number
- A597153
- Product name
- 2-Amino-4,6-dichlorobenzoic acid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA140841
- Product name
- 2-Amino-4,6-dichlorobenzoic acid
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FA140841
- Product name
- 2-Amino-4,6-dichlorobenzoic acid
- Packaging
- 250mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FA140841
- Product name
- 2-Amino-4,6-dichlorobenzoic acid
- Packaging
- 500mg
- Price
- $190
- Updated
- 2021/12/16
2-AMINO-4,6-DICHLOROBENZOIC ACID Chemical Properties,Usage,Production
Uses
2-Amino-4,6-dichlorobenzoic acid is a carboxylic acid derivative, which is mainly used in the synthesis of pharmaceutical intermediates.
Synthesis
18711-15-4
20776-63-0
General procedure for the synthesis of 2-amino-4,6-dichlorobenzoic acid from 4,6-dichlorodihydroindole-2,3-dione: 3) Preparation of intermediate I-3; At room temperature, Intermediate I-2 (5.0 g, 23.1 mmol) prepared from Example I (2) of the above isolation was dissolved in 75 mL of 1N NaOH (aq), and hydrogen peroxide (28% v/v, 10 mL) was added in batches. The reaction mixture was stirred for 2 hours and then filtered to remove the insoluble dark brown solid. Subsequently, the filtrate was carefully acidified with hydrochloric acid to pH 2. The yellow precipitate formed was collected, washed with water and dried under vacuum. The target compound 2-amino-4,6-dichlorobenzoic acid (3.90 g, 82% yield) was obtained as an ivory colored solid by recrystallization from benzene. TLC Rf = 0.1 (EtOAc:hexane = 1:1); Melting point 188-189°C; 1H NMR (DMSO-d6) δ 6.76 (d, J=1.9Hz, 1H, ArH), 6.85 (d, J=1.9Hz, 1H, ArH); MS (EI) m/e 206 [M+], 162 [M+-CO2].
References
[1] Patent: US2006/84676, 2006, A1. Location in patent: Page/Page column 7
[2] Patent: EP1650190, 2006, A1. Location in patent: Page/Page column 10
[3] Patent: WO2008/4716, 2008, A1. Location in patent: Page/Page column 25-26
[4] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 2, p. 738 - 743
[5] Patent: US2009/203708, 2009, A1. Location in patent: Page/Page column 8
2-AMINO-4,6-DICHLOROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-4,6-DICHLOROBENZOIC ACID manufacturers
- Product
- 2-AMINO-4,6-DICHLOROBENZOIC ACID 20776-63-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12