2-ACETAMIDO-6-CHLOROPURINE

Product Name: 2-ACETAMIDO-6-CHLOROPURINE
CAS No.: 7602-01-9
Chemical Name: 2-ACETAMIDO-6-CHLOROPURINE
Synonyms: 2-ACETAMIDO-6-CHLOROPURINE;2-(Acetylamino)-6-chloropurine;N-(6-Chloro-7H-purin-2-yl)acetamide;N-(6-Chloro-9H-purin-2-yl)acetamide;N-(6-chloro-5H-purin-2-yl)acetamide;Acetamide, N-(6-chloro-9H-purin-2-yl)-
CBNumber: CB7843640
Molecular Formula: C7H6ClN5O
Formula Weight: 211.61
MOL File: 7602-01-9.mol

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2-ACETAMIDO-6-CHLOROPURINE Property

Melting point:: >300 °C
Density: 1.80
pka: 9.22±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FA06027
Product name: 2-Acetamido-6-chloropurine
Packaging: 2g
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA06027
Product name: 2-Acetamido-6-chloropurine
Packaging: 5G
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 097089
Product name: N-(6-Chloro-7H-purin-2-yl)acetamide
Purity: 95+%
Packaging: 1g
Price: $114
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA06027
Product name: 2-Acetamido-6-chloropurine
Packaging: 10g
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: 1823AC
Product name: N-(6-Chloro-7H-purin-2-yl)acetamide
Packaging: 5g
Price: $185
Updated: 2021/12/16

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2-ACETAMIDO-6-CHLOROPURINE Chemical Properties,Usage,Production

Synthesis

108-24-7

10310-21-1

7602-01-9

Step 1: 2-Amino-6-chloropurine (2 g) was added to acetic anhydride (25 mL) preheated to 180 °C and the reaction was heated to reflux overnight. Upon completion of the reaction, the mixture was cooled to room temperature. The precipitate was precipitated by the addition of ether and the solid product was collected by filtration and dried. The crude product was purified by reversed-phase fast column chromatography (elution gradient: 0-60% aqueous methanol) to afford N-(6-chloro-9H-purin-2-yl)acetamide (450 mg, 17% yield) as a white solid. m/z 212 ([M+H]+) was obtained by LC-MS analysis.

References

[1] Tetrahedron Letters, 1997, vol. 38, # 8, p. 1451 - 1454
[2] Tetrahedron, 1997, vol. 53, # 34, p. 11595 - 11626
[3] Patent: WO2015/123365, 2015, A1. Location in patent: Page/Page column 140
[4] Tetrahedron, 1992, vol. 48, # 21, p. 4259 - 4270

2-ACETAMIDO-6-CHLOROPURINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-ACETAMIDO-6-CHLOROPURINE Suppliers

China 27 Germany 1 India 1 Ukraine 1 United Kingdom 4 United States 9 Global 43

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7602-01-9, 2-ACETAMIDO-6-CHLOROPURINERelated Search:

6-Chloropurine 6-CHLORO-2-(4-PHENYLBENZAMIDO)-9-(2,3-DIDEOXY-3-FLUORO-5-O-(4-PHENYLBENZOYL)-BETA-D-EYTHROPENTOFURANOSYL)-9H-PURINE AURORA KA-73 2-ACETAMIDO-6-CHLORO-9-(2,3-DIDEOXY-3-FLUORO-5-O-(METHYLBENZOYL)-BETA-D-ERYTHROPENTOFURANOSYL)-9H-PURINE AURORA KA-37 2-ACETAMIDO-6-CHLORO-9-(2',3',5'-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)PURINE 2-ACETAMIDO-6-CHLOROPURINE AURORA KA-61 2-ACETAMIDO-9-(2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)-6-CHLORO-9H-PURINE

2-ACETAMIDO-6-CHLOROPURINE

2-(Acetylamino)-6-chloropurine

N-(6-chloro-5H-purin-2-yl)acetamide

N-(6-Chloro-9H-purin-2-yl)acetamide

N-(6-Chloro-7H-purin-2-yl)acetamide

Acetamide, N-(6-chloro-9H-purin-2-yl)-

7602-01-9

C7H6ClN5O