TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE
- Product Name
- TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE
- CAS No.
- 322690-31-3
- Chemical Name
- TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE
- Synonyms
- 2-Amino-6-(Boc-amino)pyridine;TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE;tert-butyl N-(6-amino-2-pyridyl)carbamate;tert-Butyl N-(6-amino-2-pyridinyl)carbamate;tert-butyl N-(6-aminopyridin-2-yl)carbamate;2-Amino-6-(tert-butoxycarbonylamino)pyridine;2-Amino-6-(tert-butoxycarbonylamino)pyridine >tert-Butyl N-(6-amino-2-pyridinyl)carbamate 95+%;2-Amino-6-(tert-butoxycarbonylamino)pyridine;(6-Aminopyridin-2-yl)carbamic acid tert-butyl ester
- CBNumber
- CB7846595
- Molecular Formula
- C10H15N3O2
- Formula Weight
- 209.24
- MOL File
- 322690-31-3.mol
TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE Property
- Melting point:
- 125.0 to 129.0 °C
- Boiling point:
- 307.1±27.0 °C(Predicted)
- Density
- 1.202±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 12.26±0.70(Predicted)
- color
- White to Light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A2708
- Product name
- 2-Amino-6-(tert-butoxycarbonylamino)pyridine
- Purity
- >97.0%(T)
- Packaging
- 1g
- Price
- $104
- Updated
- 2024/03/01
- Product number
- A2708
- Product name
- 2-Amino-6-(tert-butoxycarbonylamino)pyridine
- Purity
- >97.0%(T)
- Packaging
- 5g
- Price
- $354
- Updated
- 2024/03/01
- Product number
- B810360
- Product name
- tert-Butyl6-Aminopyridin-2-ylcarbamate
- Packaging
- 10g
- Price
- $1100
- Updated
- 2021/12/16
- Product number
- W5411
- Product name
- tert-Butyl6-aminopyridin-2-ylcarbamate
- Packaging
- 250mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- 056362
- Product name
- tert-Butyl N-(6-amino-2-pyridinyl)carbamate
- Purity
- >95%
- Packaging
- 500mg
- Price
- $40
- Updated
- 2021/12/16
TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE Chemical Properties,Usage,Production
Uses
tert-Butyl 6-Aminopyridin-2-ylcarbamate is used in preparation of novel Macrocyclic Diacetylene compounds.Also, used in preparation of substituted Bicyclic Aza-Heterocycles and analogs as Sirtuin modulators.
Synthesis
141-86-6
24424-99-5
322690-31-3
2,6-diaminopyridine (5.00 g, 45.82 mmol) and di-tert-butyl dicarbonate ((Boc)2O) (10.99 g, 50.40 mmol) were used as raw materials and reacted in tetrahydrofuran (THF) (200 mL). 2,6-diaminopyridine was first dissolved in THF, followed by the addition of (Boc)2O, and the reaction was stirred for 12 h at room temperature. After completion of the reaction, the reaction mixture was poured into saturated aqueous sodium bicarbonate solution and the solid was collected by filtration. Purification was carried out by column chromatography (eluent ratio methanol: dichloromethane= 0.5:9.5) to give 5.2 g of 2-amino-6-(tert-butoxycarbonylamino)pyridine (compound j1) in 54% yield.
References
[1] Chemical Communications, 2008, # 35, p. 4126 - 4128
[2] Chemistry - A European Journal, 2001, vol. 7, # 13, p. 2798 - 2809
[3] Chemistry - A European Journal, 2007, vol. 13, # 19, p. 5466 - 5479
[4] Patent: KR2018/9249, 2018, A. Location in patent: Paragraph 0228; 0229
[5] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 13, p. 3493 - 3497
TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE manufacturers
- Product
- TERT-BUTYL 6-AMINOPYRIDIN-2-YLCARBAMATE 322690-31-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18