ChemicalBook > CAS DataBase List > 5-Phenyl-1H-pyrazole-3-carboxylic acid

5-Phenyl-1H-pyrazole-3-carboxylic acid

Product Name
5-Phenyl-1H-pyrazole-3-carboxylic acid
CAS No.
1134-49-2
Chemical Name
5-Phenyl-1H-pyrazole-3-carboxylic acid
Synonyms
3-Phenyl-1H<;AKOS BBS-00002542;CBI-BB ZERO/006131;CHEMBRDG-BB 4401595;CHEMBRDG-BB 7253309;TIMTEC-BB SBB006941;IFLAB-BB F0348-3292;SALOR-INT L250023-1EA;3-phenylpyrazole-5-carboxylicacid;3-phenyl-pyrazole-5-carboxylicaci
CBNumber
CB7852873
Molecular Formula
C10H8N2O2
Formula Weight
188.18
MOL File
1134-49-2.mol
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5-Phenyl-1H-pyrazole-3-carboxylic acid Property

Melting point:
250 °C
storage temp. 
2-8°C
form 
solid
InChI
InChI=1S/C10H8N2O2/c13-10(14)9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H,(H,11,12)(H,13,14)
InChIKey
QBPUOAJBMXXBNU-UHFFFAOYSA-N
SMILES
C1(=NNC(C(=O)O)=C1)C1C=CC=CC=1
CAS DataBase Reference
1134-49-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29331990
Toxicity
mouse,LDLo,intraperitoneal,1gm/kg (1000mg/kg),Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
633739
Product name
3-Phenyl-1H-pyrazole-5-carboxylic acid
Purity
97%
Packaging
1g
Price
$85
Updated
2023/06/20
AK Scientific
Product number
X9056
Product name
3-Phenyl-1H-pyrazole-5-carboxylic acid
Packaging
5g
Price
$342
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0002508
Product name
3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
1G
Price
$721.57
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0002508
Product name
3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
2.5G
Price
$983.88
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0002508
Product name
3-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
Purity
95.00%
Packaging
5G
Price
$1168.42
Updated
2021/12/16
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5-Phenyl-1H-pyrazole-3-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

White solid

Definition

ChEBI: 3-phenyl-1H-pyrazole-5-carboxylic acid is a ring assembly and a member of pyrazoles.

Synthesis

56426-35-8

1134-49-2

To a mixed solution of methyl 5-phenylpyrazole-3-carboxylate (6.02 g, 29.8 mmol) in THF with H2O (3:1, 140 mL) was added LiOH (3.42 g, 142.8 mmol) and the reaction mixture was stirred overnight at room temperature. After completion of the reaction, the mixture was poured into 2N HCl solution (150 mL) and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 3-phenyl-1H-pyrazole-5-carboxylic acid (3.2 g, 57.1% yield). The product was confirmed by mass spectrometry (EI) with molecular formula C10H8N2O2, m/z: 189.26 (MH+).

References

[1] Patent: WO2006/33943, 2006, A2. Location in patent: Page/Page column 77

5-Phenyl-1H-pyrazole-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethanol Hydrazine sulfate Potassium hydroxide Diethyl oxalate Sodium Acetophenone

Preparation Products

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5-Phenyl-1H-pyrazole-3-carboxylic acid Suppliers

Belgium 1 Canada 1 China 81 Germany 3 India 4 Russia 4 Switzerland 1 Ukraine 2 United Kingdom 3 United States 23 Global 123
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
Tel
--
Fax
--
Email
enamine@enamine.net
Country
Ukraine
ProdList
6216
Advantage
67
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View Lastest Price from 5-Phenyl-1H-pyrazole-3-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
5-Phenyl-1H-pyrazole-3-carboxylic acid 1134-49-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10 tons
Release date
2024-08-04
Career Henan Chemical Co
Product
5-Phenyl-1H-pyrazole-3-carboxylic acid 1134-49-2
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-09

1134-49-2, 5-Phenyl-1H-pyrazole-3-carboxylic acidRelated Search:

5-Phenyl-1H-pyrazole-3-carboxylic acid 5-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate Pigment Red 38 Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylate 5-(4-FLUORO-PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID,5-(4-FLUORO-PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID trisodium 4,5-dihydro-5-oxo-4-[[4-[[[3-[[2-(sulphonatooxy)ethyl]sulphonyl]phenyl]amino]carbonyl]phenyl]azo]-1-(4-sulphonatophenyl)-1H-pyrazole-3-carboxylate 1-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 5-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 1-METHYL-5-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID 4,4'-BIS[3-CARBOXY-5-OXO-1-(4-SULFOPHENYL)-2-PYRAZOLIN-4-YL]PENTAMETHINE OXONOLE DIPOTASSIUM SALT 1-(4'-Sulfophenyl)-3-carboxy-5-pyrazolone 5-(3-HYDROXY-PHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID,5-(3-HYDROXY-PHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID 1-Phenyl-1H-pyrazole-4-carboxylic acid RARECHEM AL BF 1033 2,5-DIPHENYL-2H-PYRAZOLE-3-CARBOXYLIC ACID METHYL 5-(4-CHLOROPHENYL)-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLATE METHYL 1-[4-(AMINOSULFONYL)PHENYL]-5-(4-CHLOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLATE

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