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3-Benzyloxy acetophenone

Product Name
3-Benzyloxy acetophenone
CAS No.
34068-01-4
Chemical Name
3-Benzyloxy acetophenone
Synonyms
NSC 159118;m-benzyloxyacetophenone;3-BENZYLOXYACETOPHENONE;Terbutaline Impurity 25;Terbutaline Impurity 57;Paracetamol Impurity 25;3'-Benzyloxyacetophenone;3-Benzyloxyacetophenone,97%;3'-Benzyloxyacetophenone >3''-BENZYLOXYACETOPHENONE 97%
CBNumber
CB7853522
Molecular Formula
C15H14O2
Formula Weight
226.27
MOL File
34068-01-4.mol
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3-Benzyloxy acetophenone Property

Melting point:
29-30 °C
Boiling point:
154°C/0.3mmHg(lit.)
Density 
1.0891 (rough estimate)
refractive index 
1.6530 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Low Melting Solid
color 
Light yellow
λmax
305nm(MeOH)(lit.)
CAS DataBase Reference
34068-01-4(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29145000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S549053
Product name
3''-BENZYLOXYACETOPHENONE
Purity
AldrichCPR
Packaging
50MG
Price
$30.7
Updated
2025/07/31
TCI Chemical
Product number
B4705
Product name
3'-Benzyloxyacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$75
Updated
2025/07/31
TCI Chemical
Product number
B4705
Product name
3'-Benzyloxyacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$258
Updated
2025/07/31
TRC
Product number
B285845
Product name
3-Benzyloxyacetophenone
Packaging
10g
Price
$485
Updated
2021/12/16
TRC
Product number
B285845
Product name
3-Benzyloxyacetophenone
Packaging
25g
Price
$1110
Updated
2021/12/16
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3-Benzyloxy acetophenone Chemical Properties,Usage,Production

Chemical Properties

Yellow Liquid

Synthesis

121-71-1

100-44-7

34068-01-4

Example 1 Synthesis of 3-benzyloxyacetophenone: 1 kg (7.35 mol) of 3-hydroxyacetophenone, 1.035 kg (7.5 mol) of anhydrous potassium carbonate, and 0.945 kg (7.5 mol) of benzyl chloride were dissolved in 4.1 L of acetone with mechanical stirring and heated and refluxed for 24 hrs. Subsequently, 0.1035 kg (0.75 mol) of anhydrous potassium carbonate and 0.0945 kg (0.75 mol) of benzyl chloride were added and refluxing was continued. the above additions were repeated after 72 hours and refluxing was continued to a total reaction time of 96 hours. After completion of the reaction, the reaction mixture was cooled, filtered and the filtrate was concentrated by rotary evaporator. To the concentrated filtrate was added 0.202 kg (2.0 mol) of triethylamine and stirred overnight. The reaction mixture was diluted with 1 L of ether and filtered, the filtrate was concentrated by evaporation and the residue was distilled to give 1.429 kg (86% yield) of the target product 3-benzyloxyacetophenone as an oil. Boiling point: 160°C (0.3 Torr).IR (CHCl3) spectrum showed absorption peaks located at 1695, 1605, 1595, 1493 and 1433 cm-1 .PMR (CDCl3) spectrum showed chemical shifts δ 2.52 (s, CH3), 5.03 (s, CH2) and 7.0-7.7 (m, Ph).

References

[1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988, p. 2491 - 2500
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 16, p. 3045 - 3049
[3] Tetrahedron Letters, 2007, vol. 48, # 26, p. 4627 - 4630
[4] Chemical and Pharmaceutical Bulletin, 1995, vol. 43, # 5, p. 738 - 747
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 5, p. 1537 - 1544

3-Benzyloxy acetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Benzyloxy acetophenone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-Benzyloxyacetophenone 34068-01-4
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-29
Henan Fengda Chemical Co., Ltd
Product
3-Benzyloxy acetophenone 34068-01-4
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16
Career Henan Chemical Co
Product
3-Benzyloxy acetophenone 34068-01-4
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

34068-01-4, 3-Benzyloxy acetophenoneRelated Search:


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