(R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol
- Product Name
- (R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol
- CAS No.
- 5579-16-8
- Chemical Name
- (R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol
- Synonyms
- Eppy/N;EINECS 226-961-8;epinephryl borate;Epinephrine borate;l-Adrenaline borate;l-Epinephrinyl borate;5-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-2-hydroxy 1,3,2-benzodioxaborole;(R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol;1,3,2-Benzodioxaborole-5-methanol, 2-hydroxy-α-[(methylamino)methyl]-, (αR)-
- CBNumber
- CB7885666
- Molecular Formula
- C9H12BNO4
- Formula Weight
- 209.01
- MOL File
- 5579-16-8.mol
N-Bromosuccinimide Price
- Product number
- BOR0004358
- Product name
- EPINEPHRYL BORATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.05
- Updated
- 2021/12/16
(R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol Chemical Properties,Usage,Production
Originator
Eppy,Barnes Hind,US,1961
Uses
Adrenergic.
Manufacturing Process
Epinephrine may be made by isolation from animal adrenal glands or may be
synthesized as described by Payne in Ind. Chemist, 37, 523 (1961).
It has been found that epinephrine solutions having a physiological pH and
which are stable for months in storage can be prepared by combining with the
epinephrine a small amount of sodium bisulfite, boric acid, and oxine (8-
hydroxy-quinoline) hereinafter called 8-quinolinol and adjusting the pH with
an alkali, such as sodium hydroxide, to the desired pH.
It has been found that from 0.001 to 0.1% of 8-quinolinol can be used. From
0.2 to 5% boric acid may be used. The amount of sodium bisulfite can be
varied from 0.1 to 1%. The solutions can contain from 0.1 to 4% epinephrine.
The pHs of the solutions can be adjusted to any value within the physiological
range, i.e., from 6.5 to 8.5 using any convenient alkali such as sodium
hydroxide.
brand name
Epinal (Alcon); Eppy/N(Pilkington Barnes Hind).
Therapeutic Function
Antiglaucoma
(R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2-hydroxy-alpha-[(methylamino)methyl]-1,3,2-benzodioxaborole-5-methanol Suppliers
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