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Melitracen

Product Name
Melitracen
CAS No.
5118-29-6
Chemical Name
Melitracen
Synonyms
N-7001;Dixeran;U-24973;Trausban;Melitrace;melitracen;Brn 1980107;MELITRACENE;Einecs 225-858-5;Melitracen USP/EP/BP
CBNumber
CB7909593
Molecular Formula
C21H25N
Formula Weight
291.43
MOL File
5118-29-6.mol
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Melitracen Property

Boiling point:
423.43°C (rough estimate)
Density 
0.9801 (rough estimate)
refractive index 
1.4900 (estimate)
pka
9.18±0.28(Predicted)
NIST Chemistry Reference
1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-(5118-29-6)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0007908
Product name
MELITRACEN
Purity
95.00%
Packaging
5MG
Price
$504.37
Updated
2021/12/16
AvaChem
Product number
2810B
Product name
Melitracen
Packaging
10mg
Price
$95
Updated
2021/12/16
AvaChem
Product number
2810B
Product name
Melitracen
Packaging
100mg
Price
$295
Updated
2021/12/16
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Melitracen Chemical Properties,Usage,Production

Originator

Trausabun,Lusofarma,W. Germany,1965

Uses

Antidepressant.

Definition

ChEBI: Melitracen is a member of anthracenes.

Manufacturing Process

24 g of 2-o-benzoylphenylpropanol-2 (MP 116°C) were dissolved in 250 ml of anhydrous ether and the resulting solution was added dropwise while stirring to a suspension of 0.22 mol of dimethylaminopropylmagnesium chloride in 100 ml of ether. The reaction mixture was refluxed for one hour on a steam bath, and water and dilute hydrochloric acid were added until the reaction was pH 4-5. The aqueous phase was separated and 60 ml of concentrated aqueous ammonia were added. The mixture was extracted with ether, and the ether phase was separated, dried and evaporated in a steam bath. The residue was dissolved in hot petroleum ether and the solution left standing to cool for some time, whereupon 4-dimethylamino-1-phenyl-1-[2-(2-hydroxy-2- propyl)phenyl]-butanol-1 crystallized out as white crystals which were sucked off. After drying they melted at 88°C to 90°C.
10 g of this compound were cautiously dissolved in 50 ml of concentrated sulfuric acid under cooling and the mixture was kept at room temperature for 24 hours, whereupon the reaction mixture was poured into 200 g of finely crushed ice, and concentrated aqueous ammonia was added to about pH 9, whereupon the oil which separated out was extracted with ether. The ether phase was separated, dried and the ether evaporated on a steam bath. The residue was dissolved in 20 ml of acetone and the solution neutralized with a solution of dry hydrogen chloride in ether. The white crystals of 9-γdimethylaminopropylidene-10,10-dimethyl-9,10-dihydroanthracene hydrochloride which separated out was filtered off and dried. Yield 9 g. MP 245°C to 247°C.

Therapeutic Function

Antidepressant

Melitracen Preparation Products And Raw materials

Raw materials

Preparation Products

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Melitracen Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Melitracen manufacturers

Dideu Industries Group Limited
Product
Melitracen 5118-29-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-26
Career Henan Chemical Co
Product
Melitracen 5118-29-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
KG/T
Release date
2019-12-17

5118-29-6, MelitracenRelated Search:


  • Dixeran
  • N-7001
  • Trausban
  • U-24973
  • 10563-70-9 (Hydrochloride)
  • 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl- (9ci)
  • 9-(3-Dimetilaminopropyliden)-10,10-dimetil-9,10-diidroanthracene
  • 9-(3-Dimetilaminopropyliden)-10,10-dimetil-9,10-diidroanthracene [italian]
  • Brn 1980107
  • delta-(Sup 9(10),gamma)-anthracenepropylamine, N,N,10,10-tetramethyl-
  • Einecs 225-858-5
  • Melitrace
  • MELITRACENE
  • 3-(10,10-Dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine
  • melitracen
  • 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-
  • Melitracen USP/EP/BP
  • 3-(10,10-dimethylanthracen-9-ylidene)-N,N-dimethylpropan-1-amine
  • 5118-29-6