Lysophosphatidylethanolamines, egg
- Product Name
- Lysophosphatidylethanolamines, egg
- CAS No.
- 97281-40-8
- Chemical Name
- Lysophosphatidylethanolamines, egg
- Synonyms
- L-α-lysophosphatidylethanolamine;Lysophosphatidylethanolamines, egg;Lyso-phosphatidylethanolamine (Egg);Lyso-phosphatidylethanolamine, LPE (egg;L-α-phosphatidylethanolamine (Egg, Chicken);L-α-lysophosphatidylethanolamine (Egg, Chicken);L-Α-PHOSPHATIDYLETHANOLAMINE (EGG, CHICKEN);EGG PE;3-sn-Lysophosphatidylethanolamine(Mixture of Diastereomers);L-a-Lysophosphatidylethanolamine (Egg Lyso PE) ex. Egg, 99%;L-Α-LYSOPHOSPHATIDYLETHANOLAMINE (EGG, CHICKEN);EGG LYSO PE
- CBNumber
- CB7927782
- Formula Weight
- 0
- MOL File
- Mol file
Lysophosphatidylethanolamines, egg Property
- storage temp.
- Store at -20°C
- solubility
- Chloroform: Soluble
- form
- A solid
- color
- White to off-white
- InChI
- 1S/C23H48NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(26)29-20-22(25)21-31-32(27,28)30-19-18-24/h22,25H,2-21,24H2,1H3,(H,27,28)/t22-/m1/s1
- InChIKey
- BBYWOYAFBUOUFP-JOCHJYFZSA-N
- SMILES
- [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
Safety
- WGK Germany
- WGK 3
- Hazard Classifications
- Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 25844
- Product name
- Lysophosphatidylethanolamines (egg)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 25844
- Product name
- Lysophosphatidylethanolamines (egg)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $187
- Updated
- 2024/03/01
- Product number
- 25844
- Product name
- Lysophosphatidylethanolamines (egg)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $723
- Updated
- 2024/03/01
Lysophosphatidylethanolamines, egg Chemical Properties,Usage,Production
Description
Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 and PD 98059 and the EGFR inhibitor AG-1478 . LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage. Lysophosphatidylethanolamines (egg) is a mixture of lysophosphatidylethanolamines isolated from chicken egg with fatty acyl groups of variable lengths at the sn-1 position and a hydroxy group at the sn-2 position.
Uses
Lysophosphatidyletha?nolamines, Egg is a natural Glycerophospholipid. Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
Definition
ChEBI: 1-stearoyl-sn-glycero-3-phosphoethanolamine is a 1-acyl-sn-glycero-3-phosphoethanolamine in which the acyl group is specified as stearoyl. It has a role as a human metabolite. It is a 1-acyl-sn-glycero-3-phosphoethanolamine and a lysophosphatidylethanolamine 18:0. It is functionally related to an octadecanoic acid. It is a tautomer of a 1-stearoyl-sn-glycero-3-phosphoethanolamine zwitterion.
References
[1] ATSUYOSHI NISHINA. Lysophosphatidylethanolamine in Grifola frondosa as a neurotrophic activator via activation of MAPK.[J]. Journal of Lipid Research, 2006, 47 7: 1434-1443. DOI: 10.1194/jlr.m600045-jlr200
[2] KUMIKO MAKIDE . Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol[J]. Prostaglandins & other lipid mediators, 2009, 89 3: Pages 135-139. DOI: 10.1016/j.prostaglandins.2009.04.009
[3] S B RYU. Inhibition of phospholipase D by lysophosphatidylethanolamine, a lipid-derived senescence retardant.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1997, 94 23: 12717-12721. DOI: 10.1073/pnas.94.23.12717
Lysophosphatidylethanolamines, egg Preparation Products And Raw materials
Raw materials
Preparation Products
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