ChemicalBook > CAS DataBase List > amifloxacin

amifloxacin

Product Name
amifloxacin
CAS No.
86393-37-5
Chemical Name
amifloxacin
Synonyms
AMFX;Win-49375;amifloxacin;amifloxacin USP/EP/BP;Amifloxacin (Win49375);Amifloxacin, 10 mM in DMSO;Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial;6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid;6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CBNumber
CB7942460
Molecular Formula
C16H19FN4O3
Formula Weight
334.35
MOL File
86393-37-5.mol
More
Less

amifloxacin Property

Melting point:
300 °C (decomp)
Boiling point:
532.5±60.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
6.17±0.41(Predicted)
color 
White to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0005949
Product name
AMIFLOXACIN
Purity
95.00%
Packaging
5MG
Price
$496.89
Updated
2021/12/16
Ambeed
Product number
A749227
Product name
Win49375
Purity
97%
Packaging
25mg
Price
$5
Updated
2021/12/16
More
Less

amifloxacin Chemical Properties,Usage,Production

Uses

Antibacterial.

Definition

ChEBI: Amifloxacin is a member of quinolines.

in vivo

Amifloxacin (WIN 49375) is highly active by the oral route, with 50% effective doses within two- to threefold of those obtained with parenteral medication. The effectiveness of Amifloxacin with various routes of medication is demonstrated with these experimental infections. When mice infected intraperitoneally with E. coli Vogel are medicated at 0.5-h postinfection subcutaneously, intravenously, or orally the ED50s for Amifloxacin are 0.6, 0.8, and 1.0 mg/kg, respectively[1]. Blood radioactivity peaks at 0.5 h after oral administration of [14C]Amifloxacin mesylate to rats at 20 mg/kg and is equivalent to 7.1±0.26 μg of Amifloxacin per mL. From 0.75 to 4 h, blood radioactivity decreases rapidly from 7.0±0.25 μg/mL to 1.2±0.12 μg/mL. Between 8 and 48 h the rate of decline in blood radioactivity slows and is more complex. At 48 h, the blood radioactivity is equivalent to 0.14±0.02 μg/mL. Blood levels of radioactivity after i.v. administration of [14C]Amifloxacin mesylate to rats at 20 mg/kg decrease from 29.1±0.85 μg/mL at 1.0 min to 14.4±0.52 μg/mL at 10 min. From 0.25 to 4 h blood radioactivity decreases from 13.0±0.42 μg/mL to 0.97±0.09 μg/mL in a log-linear manner. The rate of elimination from 4 to 24 h is slower and more complex. At 24 h, blood radioactivity is equivalent to 0.12±0.01 ug/mL[2].

amifloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

amifloxacin Suppliers

China 25 Germany 1 United States 3 Global 29
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
984
Advantage
55
Shenzhen Botel Biotechnology Co. Ltd.
Tel
13316949107 13316968096
Email
1979313431@qq.com
Country
China
ProdList
9564
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
More
Less

View Lastest Price from amifloxacin manufacturers

Dideu Industries Group Limited
Product
amifloxacin 86393-37-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-20

86393-37-5, amifloxacinRelated Search:

AKOS 91790 amifloxacin 6,8-Difluoro-1-(formylmethylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester Marbofloxacin

  • 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
  • 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid
  • AMFX
  • Win-49375
  • amifloxacin
  • 3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-
  • amifloxacin USP/EP/BP
  • Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial
  • 6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • Amifloxacin, 10 mM in DMSO
  • Amifloxacin (Win49375)
  • 86393-37-5