amifloxacin

Product Name: amifloxacin
CAS No.: 86393-37-5
Chemical Name: amifloxacin
Synonyms: AMFX;Win-49375;amifloxacin;amifloxacin USP/EP/BP;Amifloxacin (Win49375);Amifloxacin, 10 mM in DMSO;Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial;6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid;6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CBNumber: CB7942460
Molecular Formula: C16H19FN4O3
Formula Weight: 334.35
MOL File: 86393-37-5.mol

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amifloxacin Property

Melting point:: 300 °C (decomp)
Boiling point:: 532.5±60.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in DMSO
form: Solid
pka: 6.17±0.41(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0005949
Product name: AMIFLOXACIN
Purity: 95.00%
Packaging: 5MG
Price: $496.89
Updated: 2021/12/16

Ambeed

Product number: A749227
Product name: Win49375
Purity: 97%
Packaging: 25mg
Price: $5
Updated: 2021/12/16

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amifloxacin Chemical Properties,Usage,Production

Uses

Antibacterial.

Definition

ChEBI: Amifloxacin is a member of quinolines.

in vivo

Amifloxacin (WIN 49375) is highly active by the oral route, with 50% effective doses within two- to threefold of those obtained with parenteral medication. The effectiveness of Amifloxacin with various routes of medication is demonstrated with these experimental infections. When mice infected intraperitoneally with E. coli Vogel are medicated at 0.5-h postinfection subcutaneously, intravenously, or orally the ED₅₀s for Amifloxacin are 0.6, 0.8, and 1.0 mg/kg, respectively^[1]. Blood radioactivity peaks at 0.5 h after oral administration of [¹⁴C]Amifloxacin mesylate to rats at 20 mg/kg and is equivalent to 7.1±0.26 μg of Amifloxacin per mL. From 0.75 to 4 h, blood radioactivity decreases rapidly from 7.0±0.25 μg/mL to 1.2±0.12 μg/mL. Between 8 and 48 h the rate of decline in blood radioactivity slows and is more complex. At 48 h, the blood radioactivity is equivalent to 0.14±0.02 μg/mL. Blood levels of radioactivity after i.v. administration of [¹⁴C]Amifloxacin mesylate to rats at 20 mg/kg decrease from 29.1±0.85 μg/mL at 1.0 min to 14.4±0.52 μg/mL at 10 min. From 0.25 to 4 h blood radioactivity decreases from 13.0±0.42 μg/mL to 0.97±0.09 μg/mL in a log-linear manner. The rate of elimination from 4 to 24 h is slower and more complex. At 24 h, blood radioactivity is equivalent to 0.12±0.01 ug/mL^[2].

amifloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

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amifloxacin Suppliers

China 25 Germany 1 United States 3 Global 29

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View Lastest Price from amifloxacin manufacturers

Dideu Industries Group Limited

Product: amifloxacin 86393-37-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-20

86393-37-5, amifloxacinRelated Search:

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6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid

AMFX

Win-49375

amifloxacin

3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-

amifloxacin USP/EP/BP

Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial

6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Amifloxacin, 10 mM in DMSO

Amifloxacin (Win49375)

86393-37-5