Quinoxaline-5-sulfonylchloride
- Product Name
- Quinoxaline-5-sulfonylchloride
- CAS No.
- 844646-88-4
- Chemical Name
- Quinoxaline-5-sulfonylchloride
- Synonyms
- Quinoxaline-5-sulfonylchloride;5-Quinoxalinesulfonyl Chloride;Quinoxaline-5-sulphonyl chloride;Quinoxaline-5-sulfonylchloride ISO 9001：2015 REACH
- CBNumber
- CB7947304
- Molecular Formula
- C8H5ClN2O2S
- Formula Weight
- 228.66
- MOL File
- 844646-88-4.mol
Quinoxaline-5-sulfonylchloride Property
- storage temp.
- Storage temp. 2-8°C
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- Q765290
- Product name
- 5-QuinoxalinesulfonylChloride
- Packaging
- 10mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- 61534
- Product name
- 5-QuinoxalinesulfonylChloride
- Packaging
- 10mg
- Price
- $675
- Updated
- 2021/12/16
- Product number
- CHM0079697
- Product name
- QUINOXALINE-5-SULFONYL CHLORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
- Product number
- CHM0079697
- Product name
- QUINOXALINE-5-SULFONYL CHLORIDE
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $1334.03
- Updated
- 2021/12/16
- Product number
- Z5169
- Product name
- Quinoxaline-5-sulfonylchloride
- Packaging
- 10g
- Price
- $1357
- Updated
- 2021/12/16
Quinoxaline-5-sulfonylchloride Chemical Properties,Usage,Production
Uses
5-Quinoxalinesulfonyl Chloride is used in optimization studies relating to the identification of anthranilic sulfonamides and their activity as selective cholecystokinin-2 receptor antagonists.
Uses
Quinoxaline-5-sulfonyl chloride is used in optimization studies relating to the identification of anthranilic sulfonamides and their activity as selective cholecystokinin-2 receptor antagonists.
Synthesis
16566-20-4
844646-88-4
General procedure for the synthesis of quinoxaline-5-sulfonyl chloride from quinoxalin-5-amine: 5.3 g of 5-aminoquinoxaline was dissolved in 16 ml of concentrated hydrochloric acid and subsequently cooled to -12 °C. A diazonium salt solution was obtained by slowly adding 2.5 g of sodium nitrite solution dissolved in 10 ml of water at a temperature not exceeding -5 °C. Another 65 g of water was cooled to 1 °C, then 22 g of thionyl chloride was carefully added dropwise and 0.1 g of copper chloride was added as a catalyst to prepare to obtain a sulfur oxide solution. The diazonium salt solution was slowly added to the sulfur oxide solution in batches while maintaining a temperature not exceeding -5°C. After completion of the reaction, three extractions were carried out using 60 ml of dichloromethane. The organic phases were combined and concentrated to dryness. The crude product was purified by recrystallization from ethyl acetate to give 6.1 g of light yellow solid product in 73% yield.
References
[1] Patent: CN107805223, 2018, A. Location in patent: Paragraph 0019; 0022-0024
Quinoxaline-5-sulfonylchloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Quinoxaline-5-sulfonylchloride manufacturers
- Product
- 5-Quinoxalinesulfonyl chloride 844646-88-4
- Price
- US $2.00-6.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-ton
- Release date
- 2025-07-28
- Product
- Quinoxaline-5-sulfonylchloride 844646-88-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2020-01-07
- Product
- Quinoxaline-5-sulfonylchloride 844646-88-4
- Price
- US $1.00/KG
- Min. Order
- 1GK
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2019-12-26