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Bifemelane HCl

Product Name
Bifemelane HCl
CAS No.
62232-46-6
Chemical Name
Bifemelane HCl
Synonyms
Bifemelane HCl;Bifemelan hydrochloride;Bifemelane hydrochloride;MEAHDXWXNNDSAK-UHFFFAOYSA-N;4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochloride;inhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B
CBNumber
CB7947364
Molecular Formula
C18H23NO.ClH
Formula Weight
305.847
MOL File
62232-46-6.mol
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Bifemelane HCl Property

Melting point:
117-121°
solubility 
Soluble to 100 mM in water and to 100 mM in DMSO
form 
Powder
color 
White to yellow
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Safety

Toxicity
LD50 in mice, rats (mg/kg): 1000, 1080 orally; 173, 130 i.p. (Tobe, 1981)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
0767
Product name
Bifemelanehydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$148
Updated
2021/12/16
Tocris
Product number
0767
Product name
Bifemelanehydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$604
Updated
2021/12/16
TRC
Product number
B383203
Product name
BifemelaneHydrochloride
Packaging
1mg
Price
$85
Updated
2021/12/16
Usbiological
Product number
254757
Product name
Bifemelane hydrochloride
Packaging
10mg
Price
$389
Updated
2021/12/16
ChemScene
Product number
CS-0020979
Product name
Bifemelane(hydrochloride)
Purity
98.83%
Packaging
50mg
Price
$400
Updated
2021/12/16
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Bifemelane HCl Chemical Properties,Usage,Production

Description

Bifemelane is a nootropic reported to have antianoxic, anti-ischemic and memory enhancing activities. In man, bifemelane appears to increase cerebral blood flow, while in rodents it reverses scopolamine-induced dementia. Bifemelane has an added adrenergic component reportedly arising from norepinephrine uptake inhibition.

Originator

Mitsubishi; Eisai (Japan)

Uses

Bifemelane Hydrochloride, is an antidepressant MAO inhibitor. It has also been reported to protect neural tissues against ischemic damage and age-related neurodegeneration.

Manufacturing Process

N-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine was prepared from 2- (5-bromopentyloxy)diphenylmethane and of methylamine in ethanol is at 50°C in a sealed tube (heating for 3 hours). Ethanol and excess methylamine are distilled in vacuo, 2 N NaOH aqueous solution is added, and the reaction product is extracted with ether. Dry hydrogen chloride gas is passed into the ether solution, and the precipitate collected by filtration. Recrystallization from ethanol-ether gives N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochloride, m.p. 87.5-89.5°C.

brand name

Alnert; Celeport

Therapeutic Function

Antidepressant, Antiulcer, Nootropic

Hazard

Moderately toxic by ingestion.

storage

Desiccate at RT

Bifemelane HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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Bifemelane HCl Suppliers

Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2988
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BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
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Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
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2885349392@qq.com
Country
China
ProdList
10003
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
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QQ 3610331285
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China
ProdList
11218
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Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569262 +86-15319487004
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
3209
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ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
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3525679403@qq.com
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China
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MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58

62232-46-6, Bifemelane HClRelated Search:


  • Bifemelane HCl
  • Bifemelane hydrochloride
  • Bifemelan hydrochloride
  • MEAHDXWXNNDSAK-UHFFFAOYSA-N
  • 4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochloride
  • inhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B
  • 62232-46-6