Bifemelane HCl

Product Name: Bifemelane HCl
CAS No.: 62232-46-6
Chemical Name: Bifemelane HCl
Synonyms: Bifemelane HCl;Bifemelan hydrochloride;Bifemelane hydrochloride;MEAHDXWXNNDSAK-UHFFFAOYSA-N;Bifemelane hydrochloride, 10 mM in DMSO;4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochloride;inhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B
CBNumber: CB7947364
Molecular Formula: C18H23NO.ClH
Formula Weight: 305.847
MOL File: 62232-46-6.mol

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Bifemelane HCl Property

Melting point:: 117-121°
solubility: Soluble to 100 mM in water and to 100 mM in DMSO
form: Powder
color: White to yellow

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Safety

Toxicity: LD50 in mice, rats (mg/kg): 1000, 1080 orally; 173, 130 i.p. (Tobe, 1981)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0767
Product name: Bifemelanehydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $148
Updated: 2021/12/16

Tocris

Product number: 0767
Product name: Bifemelanehydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $604
Updated: 2021/12/16

TRC

Product number: B383203
Product name: BifemelaneHydrochloride
Packaging: 1mg
Price: $85
Updated: 2021/12/16

Usbiological

Product number: 254757
Product name: Bifemelane hydrochloride
Packaging: 10mg
Price: $389
Updated: 2021/12/16

ChemScene

Product number: CS-0020979
Product name: Bifemelane(hydrochloride)
Purity: 98.83%
Packaging: 50mg
Price: $400
Updated: 2021/12/16

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Bifemelane HCl Chemical Properties,Usage,Production

Description

Bifemelane is a nootropic reported to have antianoxic, anti-ischemic and memory enhancing activities. In man, bifemelane appears to increase cerebral blood flow, while in rodents it reverses scopolamine-induced dementia. Bifemelane has an added adrenergic component reportedly arising from norepinephrine uptake inhibition.

Originator

Mitsubishi; Eisai (Japan)

Uses

Bifemelane Hydrochloride, is an antidepressant MAO inhibitor. It has also been reported to protect neural tissues against ischemic damage and age-related neurodegeneration.

Manufacturing Process

N-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine was prepared from 2- (5-bromopentyloxy)diphenylmethane and of methylamine in ethanol is at 50°C in a sealed tube (heating for 3 hours). Ethanol and excess methylamine are distilled in vacuo, 2 N NaOH aqueous solution is added, and the reaction product is extracted with ether. Dry hydrogen chloride gas is passed into the ether solution, and the precipitate collected by filtration. Recrystallization from ethanol-ether gives N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochloride, m.p. 87.5-89.5°C.

brand name

Alnert; Celeport

Therapeutic Function

Antidepressant, Antiulcer, Nootropic

Hazard

Moderately toxic by ingestion.

storage

Desiccate at RT

Bifemelane HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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Bifemelane HCl Suppliers

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62232-46-6, Bifemelane HClRelated Search:

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Bifemelan hydrochloride

MEAHDXWXNNDSAK-UHFFFAOYSA-N

4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochloride

inhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B

Bifemelane hydrochloride, 10 mM in DMSO

62232-46-6