Bifemelane HCl
- Product Name
- Bifemelane HCl
- CAS No.
- 62232-46-6
- Chemical Name
- Bifemelane HCl
- Synonyms
- Bifemelane HCl;Bifemelan hydrochloride;Bifemelane hydrochloride;MEAHDXWXNNDSAK-UHFFFAOYSA-N;4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochloride;inhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B
- CBNumber
- CB7947364
- Molecular Formula
- C18H23NO.ClH
- Formula Weight
- 305.847
- MOL File
- 62232-46-6.mol
Bifemelane HCl Property
- Melting point:
- 117-121°
- solubility
- Soluble to 100 mM in water and to 100 mM in DMSO
- form
- Powder
- color
- White to yellow
Safety
- Toxicity
- LD50 in mice, rats (mg/kg): 1000, 1080 orally; 173, 130 i.p. (Tobe, 1981)
N-Bromosuccinimide Price
- Product number
- 0767
- Product name
- Bifemelanehydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $148
- Updated
- 2021/12/16
- Product number
- 0767
- Product name
- Bifemelanehydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $604
- Updated
- 2021/12/16
- Product number
- B383203
- Product name
- BifemelaneHydrochloride
- Packaging
- 1mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 254757
- Product name
- Bifemelane hydrochloride
- Packaging
- 10mg
- Price
- $389
- Updated
- 2021/12/16
- Product number
- CS-0020979
- Product name
- Bifemelane(hydrochloride)
- Purity
- 98.83%
- Packaging
- 50mg
- Price
- $400
- Updated
- 2021/12/16
Bifemelane HCl Chemical Properties,Usage,Production
Description
Bifemelane is a nootropic reported to have antianoxic, anti-ischemic and memory enhancing activities. In man, bifemelane appears to increase cerebral blood flow, while in rodents it reverses scopolamine-induced dementia. Bifemelane has an added adrenergic component reportedly arising from norepinephrine uptake inhibition.
Originator
Mitsubishi; Eisai (Japan)
Uses
Bifemelane Hydrochloride, is an antidepressant MAO inhibitor. It has also been reported to protect neural tissues against ischemic damage and age-related neurodegeneration.
Manufacturing Process
N-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine was prepared from 2- (5-bromopentyloxy)diphenylmethane and of methylamine in ethanol is at 50°C in a sealed tube (heating for 3 hours). Ethanol and excess methylamine are distilled in vacuo, 2 N NaOH aqueous solution is added, and the reaction product is extracted with ether. Dry hydrogen chloride gas is passed into the ether solution, and the precipitate collected by filtration. Recrystallization from ethanol-ether gives N-methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochloride, m.p. 87.5-89.5°C.
brand name
Alnert; Celeport
Therapeutic Function
Antidepressant, Antiulcer, Nootropic
Hazard
Moderately toxic by ingestion.
storage
Desiccate at RT
Bifemelane HCl Preparation Products And Raw materials
Raw materials
Preparation Products
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