Ampalex

Product Name: Ampalex
CAS No.: 154235-83-3
Chemical Name: Ampalex
Synonyms: CX 516;Ampalex;AMpakine CX516;Ampalex, >=98%;BDP-12(Ampalex);AMpalex (CX-516);CX516, 10 mM in DMSO;CX516; BDP 12; AMPAKINE CX516;SPD-420, BDP-12, CX-516, AMpalex;1-(6-Quinoxalinylcarbonyl)piperidine
CBNumber: CB81011036
Molecular Formula: C14H15N3O
Formula Weight: 241.29
MOL File: 154235-83-3.mol

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Ampalex Property

Melting point:: 88-90°C
Boiling point:: 433.1±25.0 °C(Predicted)
Density: 1.236±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform, Methanol
pka: -0.14±0.30(Predicted)
form: powder
color: white to light brown
Water Solubility: H2O: 5mg/mL, clear

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Safety

RTECS: TM2785170

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1191
Product name: CX516
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1191
Product name: CX516
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $462
Updated: 2025/07/31

Cayman Chemical

Product number: 14936
Product name: BDP-12
Purity: ≥98%
Packaging: 5mg
Price: $50
Updated: 2024/03/01

Cayman Chemical

Product number: 14936
Product name: BDP-12
Purity: ≥98%
Packaging: 10mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 14936
Product name: BDP-12
Purity: ≥98%
Packaging: 25mg
Price: $200
Updated: 2024/03/01

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Ampalex Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Uses

Ampalex is a AMPA modulator that may exhibit therapeutic properties for treating Alzheimer''s disease, schizophrenia, and mild cognitive impairment (MCI) (1,2,3,4).

Uses

It is one of a series of AMPA modulators

Definition

ChEBI: CX-516 is a N-acylpiperidine.

Biochem/physiol Actions

CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent.

in vivo

The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.)^[1].

Animal Model:	Male Lister Hooded rats (56-63 postnatal day)^[1]
Dosage:	5, 10, 20, and 40 mg/kg
Administration:	Subcutaneously
Result:	Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes. Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime.

Ampalex Preparation Products And Raw materials

Raw materials

Preparation Products

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Ampalex Suppliers

Canada 1 China 141 India 2 United Kingdom 2 United States 18 Global 164

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Scientia Pharmaceutical Technology Co., Ltd.

Tel: 21-21-54301573 13917723525
Fax: (86)21-51861981
Email: sales@scientiapharm.com
Country: China
ProdList: 263
Advantage: 62

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Beijing Yisiyan Technology Research Center

Tel: 010-56645598 13366904824
Fax: 01062230033
Email: bjkaida@163.com
Country: China
ProdList: 1618
Advantage: 59

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

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View Lastest Price from Ampalex manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ampalex 154235-83-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ampalex 154235-83-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Ampalex 154235-83-3
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

154235-83-3, AmpalexRelated Search:

ETHYL (METHYLTHIO)ACETATE Acetoin Boron trifluoride acetonitrile complex Boron trifluoride methanol complex tert-Butyllithium Haloperidol Quinoxaline Piperidine Diphenoxylate QUINOXALINE-6-CARBALDEHYDE 6-Quinoxalinecarboxamide(9CI) Ampalex

CX516; BDP 12; AMPAKINE CX516

BDP-12(Ampalex)

ABT-224,PIPERIDINE, 1-(6-QUINOXALINYLCARBONYL)-

1-(QUINOXALIN-6-YLCARBONYL)PIPERIDINE

Ampalex

Piperidin-1-yl-quinoxalin-6-ylmethanone

Methanone, 1-piperidinyl-6-quinoxalinyl-

1-(6-Quinoxalinylcarbonyl)piperidine

1-Piperidinyl-6-quinoxalinylMethanone

CX 516

SPD-420, BDP-12, CX-516, AMpalex

AMpalex (CX-516)

AMpakine CX516

6-(piperidin-1-ylcarbonyl)quinoxaline

Piperidine, 1-(6-quinoxalinylcarbonyl)-

Ampalex 1-(Quinoxalin-6-ylcarbonyl)piperidine

Ampalex, >=98%

CX516, 10 mM in DMSO

154235-83-3

Inhibitors

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

API intermediates