ChemicalBook > CAS DataBase List > Ampalex

Ampalex

Product Name
Ampalex
CAS No.
154235-83-3
Chemical Name
Ampalex
Synonyms
CX 516;Ampalex;AMpakine CX516;Ampalex, >=98%;BDP-12(Ampalex);AMpalex (CX-516);CX516, 10 mM in DMSO;CX516; BDP 12; AMPAKINE CX516;SPD-420, BDP-12, CX-516, AMpalex;1-(6-Quinoxalinylcarbonyl)piperidine
CBNumber
CB81011036
Molecular Formula
C14H15N3O
Formula Weight
241.29
MOL File
154235-83-3.mol
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Ampalex Property

Melting point:
88-90°C
Boiling point:
433.1±25.0 °C(Predicted)
Density 
1.236±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform, Methanol
pka
-0.14±0.30(Predicted)
form 
powder
color 
white to light brown
Water Solubility 
H2O: 5mg/mL, clear
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Safety

RTECS 
TM2785170
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1191
Product name
CX516
Purity
≥98% (HPLC)
Packaging
5MG
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1191
Product name
CX516
Purity
≥98% (HPLC)
Packaging
25MG
Price
$462
Updated
2025/07/31
Cayman Chemical
Product number
14936
Product name
BDP-12
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
14936
Product name
BDP-12
Purity
≥98%
Packaging
10mg
Price
$95
Updated
2024/03/01
Cayman Chemical
Product number
14936
Product name
BDP-12
Purity
≥98%
Packaging
25mg
Price
$200
Updated
2024/03/01
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Ampalex Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Uses

Ampalex is a AMPA modulator that may exhibit therapeutic properties for treating Alzheimer''s disease, schizophrenia, and mild cognitive impairment (MCI) (1,2,3,4).

Uses

It is one of a series of AMPA modulators

Definition

ChEBI: CX-516 is a N-acylpiperidine.

Biochem/physiol Actions

CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent.

in vivo

The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.)[1].

Animal Model:Male Lister Hooded rats (56-63 postnatal day)[1]
Dosage:5, 10, 20, and 40 mg/kg
Administration:Subcutaneously
Result:Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes.
Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime.

Ampalex Preparation Products And Raw materials

Raw materials

Preparation Products

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Ampalex Suppliers

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View Lastest Price from Ampalex manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Ampalex 154235-83-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Ampalex 154235-83-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
Ampalex 154235-83-3
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-09-03

154235-83-3, AmpalexRelated Search:

ETHYL (METHYLTHIO)ACETATE Acetoin Boron trifluoride acetonitrile complex Boron trifluoride methanol complex tert-Butyllithium Haloperidol Quinoxaline Piperidine Diphenoxylate QUINOXALINE-6-CARBALDEHYDE 6-Quinoxalinecarboxamide(9CI) Ampalex

  • CX516; BDP 12; AMPAKINE CX516
  • BDP-12(Ampalex)
  • ABT-224,PIPERIDINE, 1-(6-QUINOXALINYLCARBONYL)-
  • 1-(QUINOXALIN-6-YLCARBONYL)PIPERIDINE
  • Ampalex
  • Piperidin-1-yl-quinoxalin-6-ylmethanone
  • Methanone, 1-piperidinyl-6-quinoxalinyl-
  • 1-(6-Quinoxalinylcarbonyl)piperidine
  • 1-Piperidinyl-6-quinoxalinylMethanone
  • CX 516
  • SPD-420, BDP-12, CX-516, AMpalex
  • AMpalex (CX-516)
  • AMpakine CX516
  • 6-(piperidin-1-ylcarbonyl)quinoxaline
  • Piperidine, 1-(6-quinoxalinylcarbonyl)-
  • Ampalex 1-(Quinoxalin-6-ylcarbonyl)piperidine
  • Ampalex, >=98%
  • CX516, 10 mM in DMSO
  • 154235-83-3
  • Inhibitors
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API intermediates