CH 55

Product Name: CH 55
CAS No.: 110368-33-7
Chemical Name: CH 55
Synonyms: CH 55;4-[(E)-3-(3,5-Di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid;4-[(E)-3-[3,5-Bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid;(E)-4-(3-(3,5-Di-tert-butylphenyl)-3-oxoprop-1-en-1-yl)benzoic acid;(E)-4-(3-(3,5-Bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid;4-[(E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid;4-[(1E)-3-[3,5-BIS(1,1-DIMETHYLETHYL)PHENYL]-3-OXO-1-PROPENYL]BENZOIC ACID;Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-;Benzoic acid, 4-[(1E)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]-
CBNumber: CB8103738
Molecular Formula: C24H28O3
Formula Weight: 364.48
MOL File: 110368-33-7.mol

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CH 55 Property

Melting point:: 202-203.5 °C
Boiling point:: 509.5±50.0 °C(Predicted)
Density: 1.085±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 5 mg/ml
form: A crystalline solid
pka: 4.09±0.10(Predicted)
color: White to light yellow
Stability:: Light Sensitive

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18658
Product name: Ch 55
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 18658
Product name: Ch 55
Purity: ≥98%
Packaging: 5mg
Price: $98
Updated: 2024/03/01

Cayman Chemical

Product number: 18658
Product name: Ch 55
Purity: ≥98%
Packaging: 10mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 18658
Product name: Ch 55
Purity: ≥98%
Packaging: 25mg
Price: $353
Updated: 2024/03/01

Tocris

Product number: 2020
Product name: Ch55
Purity: ≥98%(HPLC)
Packaging: 10
Price: $171
Updated: 2021/12/16

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CH 55 Chemical Properties,Usage,Production

Uses

CH 55 is a synthetic analog of retinoic acid which is an effective inhibitor of angiogenesis. Retinoids and their analogs are also promising agents for cancer chemoprevention and therapy.

Definition

ChEBI: 4-[3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid is a member of chalcones.

Biological Activity

Highly potent synthetic retinoid that has high affinity for RAR- α and RAR- β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC 50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC 50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC 50 = 1 nM).

storage

Store at RT

CH 55 Preparation Products And Raw materials

Raw materials

Preparation Products

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CH 55 Suppliers

China 40 Europe 1 Germany 2 India 1 Japan 1 United Kingdom 1 United States 8 Global 54

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
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EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
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BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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Email: info@efebio.com
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Shanghai Rechem science Co., Ltd.

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Fax: QQ:1369748377
Email: sales@rechemscience.com
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MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
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Email: 1014988033@qq.com
Country: China
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Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Hubei Xinyang Medical Technology Co., Ltd

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Fax: QQ：2853117752
Email: 2853117764@qq.com
Country: China
ProdList: 8611
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110368-33-7, CH 55Related Search:

Ch-55S Ch 55G CH 55

CH 55

4-[(1E)-3-[3,5-BIS(1,1-DIMETHYLETHYL)PHENYL]-3-OXO-1-PROPENYL]BENZOIC ACID

4-[(E)-3-(3,5-Di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid

4-[(E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid

4-[(E)-3-[3,5-Bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid

(E)-4-(3-(3,5-Bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid

Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-

Benzoic acid, 4-[(1E)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]-

(E)-4-(3-(3,5-Di-tert-butylphenyl)-3-oxoprop-1-en-1-yl)benzoic acid

110368-33-7

Intracellular receptor