2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
- Product Name
- 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
- CAS No.
- 447406-52-2
- Chemical Name
- 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
- Synonyms
- 2-(3-ethylphenyl)thiazole-5-carbaldehyde;2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE;2-[4-(trifluoromethyl)phenyl]-5-thiazolecarboxaldehyde;5-Thiazolecarboxaldehyde, 2-[4-(trifluoromethyl)phenyl]-;2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE, 95+%;2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehyde
- CBNumber
- CB8104492
- Molecular Formula
- C11H6F3NOS
- Formula Weight
- 257.23
- MOL File
- 447406-52-2.mol
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- COR0001534
- Product name
- 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $203.7
- Updated
- 2021/12/16
- Product number
- P000217742
- Product name
- 2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
- Purity
- 95+%
- Packaging
- 5g
- Price
- $332
- Updated
- 2021/12/16
- Product number
- 071670
- Product name
- 2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $462
- Updated
- 2021/12/16
- Product number
- W6346
- Product name
- 2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
- Packaging
- 5g
- Price
- $506
- Updated
- 2021/12/16
- Product number
- P000217742
- Product name
- 2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $102
- Updated
- 2021/12/16
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Chemical Properties,Usage,Production
Synthesis
464192-28-7
128796-39-4
447406-52-2
2-Bromo-5-formylthiazole (525 mg, 2.73 mmol) and 4-trifluoromethylphenylboronic acid (519 mg, 2.73 mmol), catalyzed by tetrakis(triphenylphosphine)palladium(0) (95 mg, 0.082 mmol), were mixed with an aqueous solution of 2 M Na2CO3 (5.5 mL, 10.94 mmol) in dioxane (8 mL) The reaction was carried out at reflux for 20 hours. After completion of the reaction, it was cooled to room temperature and extracted with EtOAc and water by partitioning. After separation of the organic phase, it was washed with water and brine sequentially. The organic phase was dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by column chromatography with EtOAc/hexane as eluent to afford the target compound 2-(4-trifluoromethylphenyl)thiazole-5-carbaldehyde as a yellow solid (145 mg, 21% yield).
References
[1] Patent: US2007/244094, 2007, A1. Location in patent: Page/Page column 51-52
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Suppliers
- Tel
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- Country
- United Kingdom
- ProdList
- 6565
- Advantage
- 38
View Lastest Price from 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE manufacturers
- Product
- 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE 447406-52-2
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 1kg; 5kg; 10kg
- Release date
- 2020-10-27