ChemicalBook > CAS DataBase List > 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-

2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-

Product Name
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
CAS No.
2291360-73-9
Chemical Name
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
Synonyms
DKY709;NVPDKY709,NVP-DKY-709,NVP DKY709;3-(5-(1-Benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione , NVP-DKY709;2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
CBNumber
CB810671599
Molecular Formula
C25H27N3O3
Formula Weight
417.5
MOL File
2291360-73-9.mol
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2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Property

Boiling point:
661.8±55.0 °C(Predicted)
Density 
1.281±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 62.5 mg/mL (149.70 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
pka
10.73±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Chemical Properties,Usage,Production

Biological Activity

NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.

References

[1]. Simone BONAZZI, et al. Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives. WO2020128972 A1.

2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]- Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696,15000506266 15000506266
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China
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Shanghaizehan biopharma technology co., Ltd.
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Suzhou Unite pharmTech Co., Ltd ,
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Shanghai Chaolan Chemical Technology Center
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DC Chemicals
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2291360-73-9, 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-Related Search:


  • 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-
  • NVPDKY709,NVP-DKY-709,NVP DKY709
  • DKY709
  • 3-(5-(1-Benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione , NVP-DKY709
  • 2291360-73-9