5-BROMO-2,3-DIAMINOFLUOROBENZENE
- Product Name
- 5-BROMO-2,3-DIAMINOFLUOROBENZENE
- CAS No.
- 517920-69-3
- Chemical Name
- 5-BROMO-2,3-DIAMINOFLUOROBENZENE
- Synonyms
- 5-Bromo-3-fluorobenzene-1,2-diamine;5-BROMO-2,3-DIAMINOFLUOROBENZENE;3-Fluoro-5-Bromo-Phenylenediamine;5-Bromo-3-fluoro-1,2-benzenediamine;5-Bromo-3-fluorobenzene-1,2-diamine97%;5-Bromo-3-fluorobenzene-1,2-diamine 97%;1, 2- Benzenediamine, 5- bromo- 3- fluoro-;5-Bromo-3-fluorophenylene-1,2-diamine, 5-Bromo-2,3-diamino-1-fluorobenzene
- CBNumber
- CB8106805
- Molecular Formula
- C6H6BrFN2
- Formula Weight
- 205.03
- MOL File
- 517920-69-3.mol
5-BROMO-2,3-DIAMINOFLUOROBENZENE Property
- Boiling point:
- 274.8±35.0 °C(Predicted)
- Density
- 1.792±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- form
- crystalline solid
- pka
- 2.07±0.10(Predicted)
- color
- Faint red to faint purple to light brown
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2921599090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- B700335
- Product name
- 5-Bromo-3-fluorobenzene-1,2-diamine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC5177
- Product name
- 5-Bromo-3-fluorobenzene-1,2-diamine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $27
- Updated
- 2021/12/16
- Product number
- 3630-B-07
- Product name
- 5-Bromo-2,3-diaminofluorobenzene
- Purity
- 97%
- Packaging
- 250mg
- Price
- $29
- Updated
- 2021/12/16
- Product number
- V6352
- Product name
- 5-Bromo-3-fluorobenzene-1,2-diamine
- Packaging
- 250mg
- Price
- $30
- Updated
- 2021/12/16
- Product number
- 091050
- Product name
- 5-Bromo-3-fluorobenzene-1,2-diamine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $220
- Updated
- 2021/12/16
5-BROMO-2,3-DIAMINOFLUOROBENZENE Chemical Properties,Usage,Production
Synthesis
517920-70-6
517920-69-3
General procedure for the synthesis of 5-bromo-3-fluorobenzene-1,2-diamine from 2-fluoro-4-bromo-6-nitroaniline: to a solution of 4-bromo-2-fluoro-6-nitroaniline (0.5 g, 2.1 mmol) in tetrahydrofuran (THF, 4.6 mL) was added ethanol (EtOH, 4.6 mL) and water (H2O, 1.5 mL), followed by addition of iron powder (0.6 g , 10.6 mmol) and ammonium chloride (0.17 g, 3.2 mmol). The reaction mixture was stirred at 95 °C for 22 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered through diatomaceous earth. The solid residue was washed with ethanol until the filtrate was colorless. The filtrates were combined, concentrated under reduced pressure, and the residue was dissolved in ethyl acetate (EtOAc), washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate (Na2SO4), filtered, and concentrated under reduced pressure to give the title compound, 5-bromo-3-fluorobenzene-1,2-diamine (0.43 g, 99% yield), as a brown waxy solid.
References
[1] Patent: WO2012/83170, 2012, A1. Location in patent: Page/Page column 156-157
[2] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 116-117
[3] Patent: CN108314680, 2018, A. Location in patent: Paragraph 0472-0476
5-BROMO-2,3-DIAMINOFLUOROBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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