Quinupristin

Product Name: Quinupristin
CAS No.: 120138-50-3
Chemical Name: Quinupristin
Synonyms: RP 68888;RP 57669;Antibiotic RP 57669;Quinupristin Mesylate;Quinupristin(RP-57669);Quinupristin Discontinued;Quinupristin/dalfopristin,Quinupristin,antibiotic,Quinupristin-dalfopristin,streptogramin,Inhibitor,Bacterial,inhibit;4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1;Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]methyl]-4-oxo-2-piperidinecarboxylic acid]-
CBNumber: CB81073487
Molecular Formula: C53H67N9O10S
Formula Weight: 1022.23
MOL File: 120138-50-3.mol

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Quinupristin Property

Melting point:: ~200°

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Safety

Hazardous Substances Data: 120138-50-3(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19764
Product name: Quinupristin (mesylate)
Purity: ≥98%
Packaging: 1mg
Price: $255
Updated: 2024/03/01

Cayman Chemical

Product number: 19764
Product name: Quinupristin (mesylate)
Purity: ≥98%
Packaging: 5mg
Price: $952
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: API0004691
Product name: QUINUPRISTIN
Purity: 95.00%
Packaging: 500MG
Price: $1963.5
Updated: 2021/12/16

ApexBio Technology

Product number: C5450
Product name: Quinupristin(mesylate)
Packaging: 1mg
Price: $276
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004691
Product name: QUINUPRISTIN
Purity: 95.00%
Packaging: 50MG
Price: $750.75
Updated: 2021/12/16

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Quinupristin Chemical Properties,Usage,Production

Description

Quinupristin is a streptogramin antibiotic that blocks peptide bond formation and peptide extension in bacteria. Quinupristin is usually combined with another streptogramin antibiotic, dalfopristin , to produce quinupristin-dalfopristin complex , known commercially as Synercid. While both quinupristin and dalfopristin have bacteriostatic effects, they act synergistically to kill Gram-positive bacteria, as well as some Gram-negative and anaerobic bacteria.

Uses

Quinupristin is a semi-synthetic analogue of virginiamycin B (ostreogyrcin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

Uses

Quinupristin is a semi-synthetic analogue of virginiamycin B (ostreogrycin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

Uses

Semisynthetic depsipeptide type I streptogramin. An antibacterial agent.

Quinupristin Preparation Products And Raw materials

Raw materials

Preparation Products

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Quinupristin Suppliers

Canada 1 China 37 Germany 1 India 1 United Kingdom 1 United States 5 Global 46

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View Lastest Price from Quinupristin manufacturers

Hebei Duling International Trade Co. LTD

Product: Quinupristin 120138-50-3
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-04-24

120138-50-3, QuinupristinRelated Search:

N-Acetyl-4-piperidone C-(1-METHYL-PIPERIDIN-2-YL)-METHYLAMINE DIISOBUTYL SULFIDE 3-HYDROXYPICOLINAMIDE 1-ETHYL-3-METHYL-4-PIPERIDONE 1-BUTYL-4-PIPERIDONE AC-DL-PHG-OH Quinupristin-dalfopristin ISO-BUTYL ISO-PROPYL SULFIDE CHEMBRDG-BB 9070682 1-ethylpiperidine-2-methylamine Methyl[(1-methylpiperidin-2-yl)methyl]amine ETHYL[(1-METHYLPIPERIDIN-2-YL)METHYL]AMINE 1-butyrylpiperidin-4-one Quinupristin 2-(2-methylpiperidin-1-yl)ethanamine AC-ALA-ALA-ALA-ALA-OME N-methylpiperidine-2-carboxamide

4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1

Antibiotic RP 57669

RP 57669

RP 68888

Quinupristin(RP-57669)

Quinupristin Discontinued

Quinupristin Mesylate

Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]methyl]-4-oxo-2-piperidinecarboxylic acid]-

Quinupristin/dalfopristin,Quinupristin,antibiotic,Quinupristin-dalfopristin,streptogramin,Inhibitor,Bacterial,inhibit

120138-50-3

C53H67N9O10S

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