ChemicalBook > CAS DataBase List > 1,3-Dioxo-2-isoindolineaceticacid

1,3-Dioxo-2-isoindolineaceticacid

Product Name
1,3-Dioxo-2-isoindolineaceticacid
CAS No.
6296-53-3
Chemical Name
1,3-Dioxo-2-isoindolineaceticacid
Synonyms
3-AcetaMidophthalic anhydride;N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetaMide;3-AcetylaMinophthalic Anhydride;NSC 17048;NSC 16261;1,3-Dioxo-2;Apremilast inter1;Apremilast Impurity 43;Apremilast Intermediates1;Apremilast Intermediate III
CBNumber
CB81073957
Molecular Formula
C10H7NO4
Formula Weight
205.17
MOL File
6296-53-3.mol
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1,3-Dioxo-2-isoindolineaceticacid Property

Melting point:
185-186℃
Boiling point:
489.1±28.0 °C(Predicted)
Density 
1.512±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
form 
Solid
pka
13.81±0.20(Predicted)
color 
Off-White to Pale Yellow
Stability:
Moisture Sensitive
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Safety

HS Code 
2924.29.7790
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2804
Product name
3-Acetamidophthalic Anhydride
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
A2804
Product name
3-Acetamidophthalic Anhydride
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$47
Updated
2024/03/01
TRC
Product number
A170980
Product name
3-AcetylaminophthalicAnhydride
Packaging
10g
Price
$1190
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0005999
Product name
N-(1,3-DIOXO-1,3-DIHYDRO-2-BENZOFURAN-4-YL)ACETAMIDE
Purity
95.00%
Packaging
5G
Price
$1212.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0005999
Product name
N-(1,3-DIOXO-1,3-DIHYDRO-2-BENZOFURAN-4-YL)ACETAMIDE
Purity
95.00%
Packaging
10G
Price
$1819.13
Updated
2021/12/16
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1,3-Dioxo-2-isoindolineaceticacid Chemical Properties,Usage,Production

Uses

3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2

1,3-Dioxo-2-isoindolineaceticacid Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Dioxo-2-isoindolineaceticacid Suppliers

Americas 1 China 238 Europe 1 Germany 2 India 49 Japan 1 Switzerland 1 United Kingdom 2 United States 13 Global 308
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from 1,3-Dioxo-2-isoindolineaceticacid manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
1,3-Dioxo-2-isoindolineaceticacid 6296-53-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2024-03-05
WUHAN FORTUNA CHEMICAL CO., LTD
Product
1,3-Dioxo-2-isoindolineaceticacid 6296-53-3
Price
US $0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
10kg/month
Release date
2021-12-17
Hangzhou ICH Biofarm Co., Ltd
Product
N-Phthaloylglycine 6296-53-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18

6296-53-3, 1,3-Dioxo-2-isoindolineaceticacidRelated Search:

Cyclohexanone Hydantoin (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine Apremilast Impurity E Apremilast Impurity 1 (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 1/2 Apremilast Impurity 8 Apremilast Impurity 13 Apremilast Impurity 28 Apremilast Impurity 25 Apremilast-d8 (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide APST-ZA Apremilast Impurity 2 Apremilast Impurity 9 Apremilast impurity 18 Apremilast Impurity 15

  • N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide
  • AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
  • 3-AcetylaMino-phthalsaeure-anhydrid
  • 3-AcetaMidophthalic anhydride
  • 1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3
  • 3-AcetylaMinophthalic Anhydride
  • N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide
  • NSC 16261
  • NSC 17048
  • N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)acetaMide
  • N-(1,3-Dioxo-4-isobenzofuranyl)acetaMide
  • Apremilast Intermediate III
  • 3-Acetamidophthalic anhydride NSC 16261
  • N-(1,3-dioxo-2-benzofuran-4-yl)acetamide
  • N-(1,3-Dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide
  • 1,3-Dioxo-2
  • RE-EXPORT OF REJECTED IMPORT MATERIAL: N -(1,3-DIHYDROIS OBENZOFURAN-4-YL) ACETAM IDE SYNONYM: 3-ACETAMIDOPHTHALIC ANHYDRI
  • Apremilast inter1
  • Apremilast Intermediates1
  • N-(1,3-Dioxo-1,3-dihydro-2- benzofuran-4-yl)acetamide Apremilast
  • N-(1,3-dioxo-1,3-dihydroisobenzofuran-4-yl)
  • Apremilast Impurity 43
  • 3-Aceta amido pthalic anhydride
  • 3-Acetamidophthalic Anhydride &gt
  • RSSYY(Perospirone Hydrochloride Hydrate)-7
  • 4-Acetamido-1,3-isobenzofurandione
  • 6296-53-3