Torbafylline
- Product Name
- Torbafylline
- CAS No.
- 105102-21-4
- Chemical Name
- Torbafylline
- Synonyms
- HWA-448;Torbafylline;Torbafylline, 10 mM in DMSO;7-(Ethoxymethyl)-1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione, 7-(ethoxymethyl)-3,7-dihydro-1-(5-hydroxy-5-methylhexyl)-3-methyl-
- CBNumber
- CB81116166
- Molecular Formula
- C16H26N4O4
- Formula Weight
- 338.4
- MOL File
- 105102-21-4.mol
Torbafylline Property
- Boiling point:
- 534.7±60.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- pka
- 15.28±0.29(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0012704
- Product name
- TORBAFYLLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.1
- Updated
- 2021/12/16
Torbafylline Chemical Properties,Usage,Production
Uses
Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis[1].
References
[1] Okyayuz-Baklouti I. The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle. Eur J Pharmacol. 1989 Jul 4;166(1):75-86. DOI:10.1016/0014-2999(89)90685-7
Torbafylline Preparation Products And Raw materials
Raw materials
Preparation Products
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