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Torbafylline

Product Name
Torbafylline
CAS No.
105102-21-4
Chemical Name
Torbafylline
Synonyms
HWA-448;Torbafylline;Torbafylline, 10 mM in DMSO;7-(Ethoxymethyl)-1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione;1H-Purine-2,6-dione, 7-(ethoxymethyl)-3,7-dihydro-1-(5-hydroxy-5-methylhexyl)-3-methyl-
CBNumber
CB81116166
Molecular Formula
C16H26N4O4
Formula Weight
338.4
MOL File
105102-21-4.mol
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Torbafylline Property

Boiling point:
534.7±60.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
pka
15.28±0.29(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0012704
Product name
TORBAFYLLINE
Purity
95.00%
Packaging
5MG
Price
$498.1
Updated
2021/12/16
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Torbafylline Chemical Properties,Usage,Production

Uses

Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis[1].

References

[1] Okyayuz-Baklouti I. The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle. Eur J Pharmacol. 1989 Jul 4;166(1):75-86. DOI:10.1016/0014-2999(89)90685-7

Torbafylline Preparation Products And Raw materials

Raw materials

Preparation Products

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Torbafylline Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Jinan ponder chemical co. LTD
Tel
0531-0000
Email
thinklifescience@163.com
Country
China
ProdList
19689
Advantage
58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd
Tel
1701086315
Fax
1701086315@qq.com
Email
dexuanpharma@126.com
Country
China
ProdList
9475
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11972
Advantage
58
Beijing Boorsen Biotechnology Co., Ltd
Tel
400-901-9800 18611424007
Email
cis@bioss.com.cn
Country
China
ProdList
9185
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29431
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6813
Advantage
58
Shanghai Amole Biotechnology Co., Ltd.
Tel
18916360931 18916360931
Email
2596183085@qq.com
Country
China
ProdList
17238
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58

105102-21-4, TorbafyllineRelated Search:


  • Torbafylline
  • 7-(Ethoxymethyl)-1-(5-hydroxy-5-methylhexyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
  • HWA-448
  • 1H-Purine-2,6-dione, 7-(ethoxymethyl)-3,7-dihydro-1-(5-hydroxy-5-methylhexyl)-3-methyl-
  • Torbafylline, 10 mM in DMSO
  • 105102-21-4
  • C16H26N4O4