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Pirmenol

Product Name
Pirmenol
CAS No.
68252-19-7
Chemical Name
Pirmenol
Synonyms
(±)-Pirmenol;Pirmenol (Cl-845);Pirmenol, 10 mM in DMSO;2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, cis-;rel-4-((2S,6R)-2,6-Dimethylpiperidin-1-yl)-1-phenyl-1-(pyridin-2-yl)butan-1-ol;2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, cis-(+-)-;2-Pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl-, rel-;2-Pyridinemethanol, a-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-a-phenyl-, rel- (9CI)
CBNumber
CB81116681
Molecular Formula
C22H30N2O
Formula Weight
338.49
MOL File
68252-19-7.mol
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Pirmenol Property

Melting point:
70-71°
Boiling point:
499.6±45.0 °C(Predicted)
Density 
1.046±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 2mg/mL,DMSO: 5mg/mL,Ethanol: 10mg/mL,Ethanol:PBS (pH 7.2) (1:5): 0.16mg/mL
form 
A solid
pka
12.66±0.29(Predicted)
color 
White to v. dark grey
InChI
1S/C22H30N2O/c1-18-10-8-11-19(2)24(18)17-9-15-22(25,20-12-4-3-5-13-20)21-14-6-7-16-23-21/h3-7,12-14,16,18-19,25H,8-11,15,17H2,1-2H3/t18-,19+,22
InChIKey
APUDBKTWDCXQJA-QIDMFYOTSA-N
SMILES
OC(C1=CC=CC=C1)(C2=NC=CC=C2)CCCN3[C@@H](C)CCC[C@H]3C
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3555
Product name
Pirmenol
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$89.7
Updated
2026/04/30
Sigma-Aldrich
Product number
SML3555
Product name
Pirmenol
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$289
Updated
2026/04/30
Cayman Chemical
Product number
29042
Product name
Pirmenol
Purity
≥98%
Packaging
1mg
Price
$41
Updated
2026/04/30
Cayman Chemical
Product number
29042
Product name
Pirmenol
Purity
≥98%
Packaging
5mg
Price
$167
Updated
2026/04/30
Cayman Chemical
Product number
29042
Product name
Pirmenol
Purity
≥98%
Packaging
10mg
Price
$293
Updated
2026/04/30
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Pirmenol Chemical Properties,Usage,Production

Uses

Cardiac depressant (anti-arrhythmic).

Definition

ChEBI: Pirmenol is a racemate.

brand name

Pirmavar (Parke-Davis).

Biological Activity

Pirmenol is an antiarrhythmic agent class Ia th at exhibit long half-life and low toxicities. Pirmenol suppresses premature ventricular contractions in human studies.

in vivo

Pirmenol (2.5 and 5 mg/kg, p.o.) is effective against the arrhythmias in conscious, coronary artery ligated dogs[4].
Pirmenol (rats) shows LD50s of 359.9 mg/kg (p.o), 23.6 mg/kg (i.v.)[2].
Pirmenol (mice) shows LD50s of 215.5 mg/kg (p.o), 20.8 mg/kg (i.v.)[2].

Animal Model:Conscious, coronary artery ligated dogs[4]
Dosage:Oral administration (p.o.)
Administration:2.5 and 5 mg/kg
Result:Restored normal sinus rhythm, and showed a long duration of activity, wide safety margin.

Pirmenol Preparation Products And Raw materials

Raw materials

Preparation Products

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Pirmenol Suppliers

China 31 United Kingdom 1 United States 6 Global 38
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai BetterBioChem Co., Ltd.
Tel
+86-18017644823
Fax
- QQ：1910610264
Email
sales@betterbiochem.com
Country
China
ProdList
325
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58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
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58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58

68252-19-7, PirmenolRelated Search:

Pirmenol hydrochloride 1-PHENYL-1-(2-PYRIDYL)ETHANOL 4-DIISOPROPYLAMINO-1-BUTANOL Pirmenol

  • 2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, cis-
  • 2-Pyridinemethanol, a-[3-(2,6-dimethyl-1-piperidinyl)propyl]-a-phenyl-, cis-(+-)-
  • 2-Pyridinemethanol, a-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-a-phenyl-, rel- (9CI)
  • 2-Pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl-, rel-
  • Pirmenol (Cl-845)
  • rel-4-((2S,6R)-2,6-Dimethylpiperidin-1-yl)-1-phenyl-1-(pyridin-2-yl)butan-1-ol
  • Pirmenol, 10 mM in DMSO
  • (±)-Pirmenol
  • 68252-19-7