Sulopenem

Product Name: Sulopenem
CAS No.: 120788-07-0
Chemical Name: Sulopenem
Synonyms: CP-70429;Sulopenem;CP-65207-S;Sulopenem USP/EP/BP;(S)-3-[[(5R)-2-Carboxy-6β-[(R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]tetrahydrothiophene 1-oxide;(5R,6S)-6-((R)-1-hydroxyethyl)-3-(((1R)-1-oxidotetrahydrothiophen-3-yl)thio)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-, (5R,6S)-
CBNumber: CB81116702
Molecular Formula: C12H15NO5S3
Formula Weight: 349.45
MOL File: 120788-07-0.mol

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Sulopenem Property

Boiling point:: 693.1±55.0 °C(Predicted)
Density: 1.74±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 3.88±0.40(Predicted)
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S789485
Product name: Sulopenem
Packaging: 0.5mg
Price: $415
Updated: 2021/12/16

ChemScene

Product number: CS-0025618
Product name: Sulopenem
Purity: 98.06%
Packaging: 5mg
Price: $200
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006068
Product name: SULOPENEM
Purity: 95.00%
Packaging: 5MG
Price: $500.13
Updated: 2021/12/16

DC Chemicals

Product number: DC32221
Product name: CP-70429
Packaging: 250mg
Price: $1600
Updated: 2021/12/16

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Sulopenem Chemical Properties,Usage,Production

Description

Sulopenem is a parenteral penem that demonstrates high activity against Gram-positive, Gram-negative, and anaerobic bacteria. Since it is stable in relation to renal dehydropeptidase I, it does not require concomitant administration of an inhibitor of this enzyme.

Uses

Antibacterial.

Uses

Sulopenem is a β-Lactamase inhibitor which is used in treatment of microbial infections. It is an important reagent for many drugs synthesized against bacterial infections.

Mechanism of action

Sulopenem is one of the penems and, as such, interacts with penicillin-binding proteins (PBPs). From in vitro studies, sulopenem has shown a high affinity for PBP1a, 1b, 2, and 3 in E. coli.

Pharmacokinetics

When 1 g of CP-65,207 [containing 46.3% of S-isomer (sulopenem) and 53.7% of R-isomer] was administered by 10-minute intravenous infusions, the peak concentration of sulopenem in serum was 36.0 mg/ ml, its half-life was 52.8 minutes, and the area under the serum concentration-versus-time curve (AUC) from 0 to 8 hours was 21.0 mg/ml per hour.

Sulopenem Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulopenem Suppliers

China 36 India 1 United Kingdom 3 United States 6 Global 46

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Shanghai Biolang biotechnology Co.,Ltd

Tel: 17764003753
Fax: 13669031409
Email: 2326587775@qq.com
Country: China
ProdList: 188
Advantage: 55

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Kaixin Chemical (Hong Kong) Limited

Tel: 010-88886666-01 13112345678
Fax: CDXH21@126.com
Email: loyson@tcypharm.com
Country: China
ProdList: 595
Advantage: 55

Wellman Pharmaceutical Group Limited

Tel: 027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 4029
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

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View Lastest Price from Sulopenem manufacturers

Career Henan Chemica Co

Product: Sulopenem 120788-07-0
Price: US $0.01/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 5kg; 10kg
Release date: 2020-10-28

120788-07-0, SulopenemRelated Search:

N-(3-MERCAPTO-2-METHYLPROPANOYL)GLYCINE (AZETIDIN-3-YL)METHANOL Sulopenem Meropenem Faropenem sodium Imipenem

(S)-3-[[(5R)-2-Carboxy-6β-[(R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]tetrahydrothiophene 1-oxide

CP-65207-S

CP-70429

Sulopenem

(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-, (5R,6S)-

Sulopenem USP/EP/BP

(5R,6S)-6-((R)-1-hydroxyethyl)-3-(((1R)-1-oxidotetrahydrothiophen-3-yl)thio)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

120788-07-0

C12H15NO5S3

API