ChemicalBook > CAS DataBase List > (R)-3-Benzyloxy-Pyrrolidine Hydrochloride

(R)-3-Benzyloxy-Pyrrolidine Hydrochloride

Product Name
(R)-3-Benzyloxy-Pyrrolidine Hydrochloride
CAS No.
927819-90-7
Chemical Name
(R)-3-Benzyloxy-Pyrrolidine Hydrochloride
Synonyms
(3R)-3-benzyloxypyrrolidine;(R)-3-Benzyloxy Pyrrolidine Hcl;3-phenylmethoxypyrrolidine hydrochloride;(R)-3-BENZYLOXY-PYRROLIDINE HYDROCHLORIDE;(3R)-3-(benzyloxy)pyrrolidine hydrochloride
CBNumber
CB81118928
Molecular Formula
C11H16ClNO
Formula Weight
213.71
MOL File
927819-90-7.mol
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(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Property

storage temp. 
Sealed in dry,Room Temperature
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B130245
Product name
(R)-3-BENZYLOXY-PYRROLIDINEHYDROCHLORIDE
Packaging
100mg
Price
$60
Updated
2021/12/16
Activate Scientific
Product number
AS35806
Product name
(R)-3-Benzyloxypyrrolidine hydrochloride
Purity
95+% ee
Packaging
1g
Price
$229
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0004337
Product name
(R)-3-BENZYLOXY-PYRROLIDINE HYDROCHLORIDE
Purity
95.00%
Packaging
1G
Price
$263.55
Updated
2021/12/16
Activate Scientific
Product number
AS35806
Product name
(R)-3-Benzyloxypyrrolidine hydrochloride
Purity
95+% ee
Packaging
5G
Price
$655
Updated
2021/12/16
AK Scientific
Product number
W9561
Product name
(R)-3-Benzyloxypyrrolidinehydrochloride
Packaging
5g
Price
$728
Updated
2021/12/16
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(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Chemical Properties,Usage,Production

Uses

(R)-3-Benzyloxy-Pyrrolidine Hydrochloride is an important organic reagent that can be used as a building block for the synthesis of many organic compounds, such as (R)-ethyl 4-(3-(benzyloxy)pyrrolidin-1-yl)butanoate.

Synthesis

After N-tert-butoxycarbonyl-(R)-3-benzyloxypyrrolidine separately obtained was dissolved in isopropanol and heated to 40 °C, isopropanol solution of hydrogen chloride was dropped for 6 hours. After the reaction finished, the mixture was cooled to 23 °C and was concentrated to distil the solvent away. Further, ethyl acetate was added and the mixture was concentrated, thereby obtaining a concentrate in an amount of about. Then, the concentrate was heated to 40 °C, and isopropanol was added until (R)-3-benzyloxypyrrolidine hydrochloride which had been separated as an oily substance became completely dissolved. After (R) -3-benzyloxypyrrolidine hydrochloride was crystallized by gradually cooling the solution and suitably adding a seed crystal, hexane was further added. At the time, crystallization solvent was in a following proportion: isopropanol/ethyl acetate/hexane = 1/71.5/71.5. A deposited crystal was subjected to filtration under reduced pressure, and the resultant wet crystal was washed with ethyl acetate, and then a wet crystal was dried under reduced pressure, thereby obtaining dry crystal of (R)-3-benzyloxypyrrolidine hydrochloride (yield of 82 %, purity of 99.8 %).

(R)-3-Benzyloxy-Pyrrolidine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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927819-90-7, (R)-3-Benzyloxy-Pyrrolidine HydrochlorideRelated Search:


  • (R)-3-BENZYLOXY-PYRROLIDINE HYDROCHLORIDE
  • (R)-3-Benzyloxy Pyrrolidine Hcl
  • (3R)-3-(benzyloxy)pyrrolidine hydrochloride
  • (3R)-3-benzyloxypyrrolidine
  • 3-phenylmethoxypyrrolidine hydrochloride
  • 927819-90-7