ChemicalBook > CAS DataBase List > H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

Product Name
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
CAS No.
350228-37-4
Chemical Name
H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
Synonyms
BACE-IN-1;P10-P4' StatVal;KTEEISEVN-STA-VAEF;KTEETSEVN(STAT)VAEF;B-SECRETASE INHIBITOR;KTEEISEVN [STATINE] VAEF;BETA-SECRETASE INHIBITOR;BETA-SECRETASE INHIBITOR 1;APP BETA-SECRETASE INHIBITOR;?-Secretase Inhibitor 1 - 1 mg
CBNumber
CB8114228
Molecular Formula
C73H118N16O27
Formula Weight
1651.81
MOL File
350228-37-4.mol
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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Property

Boiling point:
1976.1±65.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
powder
pka
3.48±0.10(Predicted)
color 
white
Sequence
Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FA109378
Product name
(Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging
1mg
Price
$164
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109378
Product name
(Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging
2mg
Price
$285
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109378
Product name
(Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging
5mg
Price
$570
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000802
Product name
AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR
Purity
95.00%
Packaging
1MG
Price
$764.03
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA109378
Product name
(Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging
10mg
Price
$991.3
Updated
2021/12/16
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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Chemical Properties,Usage,Production

Uses

β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1].

References

[1] Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254.
[2] Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450. DOI:10.1002/chem.202300450

H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Suppliers

CHINA 68 France 1 Germany 1 Japan 3 Switzerland 1 The Netherlands 1 United Kingdom 4 United States 10 Global 89
Brunschwig chemie
Tel
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Fax
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Email
brunschwig@brunschwig.nl
Country
The Netherlands
ProdList
4996
Advantage
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350228-37-4, H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OHRelated Search:

STATINE H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

  • AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR
  • A4 PROTEIN PRECURSOR770 (662-675)
  • BACE-IN-1
  • LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-[STATINE]-VAL-ALA-GLU-PHE
  • LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATINE)-VAL-ALA-GLU-PHE-OH
  • LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATIN)-VAL-ALA-GLU-PHE-OH
  • LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE
  • KTEETSEVN(STAT)VAEF
  • KTEEISEVN [STATINE] VAEF
  • KTEEISEVN-STA-VAEF
  • KTEEISEVN-Sta-VAEF(Sta=statine)
  • P10-P4' StatVal
  • L-Lysyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-alpha-glutamyl-L-phenylalanine
  • (Asn670,Sta671,Val672)-AMyloid b/A4 Protein Precursor770 (662-675)
  • H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
  • BETA-SECRETASE INHIBITOR
  • BETA-SECRETASE INHIBITOR 1
  • B-SECRETASE INHIBITOR
  • [ASN670, STA671, VAL672]AMYLOID-BETA
  • (ASN670,STA671,VAL672)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (662-675)
  • (ASN670,STA671,VAL672)-APP770 (662-675)
  • APP BETA-SECRETASE INHIBITOR
  • L-Phenylalanine, L-lysyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-α-glutamyl-
  • (Asn670,Sta671,Val672)-Amyloid β/A4 Protein Precursor770 (662-675)
  • Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)
  • (Asn???,Sta??1,Val??2)-Amyloid β/A4 Protein Precursor??? (662-675) ammonium salt
  • (Asn???,Sta???,Val???)-Amyloid β/A4 Protein Precursor??? (662-675) ammonium salt
  • ?-Secretase Inhibitor 1 - 1 mg
  • (Asn670, Sta671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium
  • (Asn670,Sta671,Va672)-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt
  • Lys-THR-E-Glu-I-S-E-Val-ASN-STA-Val-A-E-Phe
  • 350228-37-4
  • C73H118N16O27
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • Enzymes, Inhibitors, and Substrates
  • R to Z
  • BioChemical
  • Biochemicals and Reagents
  • beta-Secretase
  • Pepetides
  • peptides
  • Amyloid beta-peptide and related
  • peptide
  • beta-SecretaseNeurobiology
  • β-SecretaseEnzyme Inhibitors by Enzyme
  • Alzheimers and Neurodegenerative Disease Research
  • Neurodegenerative Disease Peptides
  • Other Alzheimer Peptides
  • OtherNeuropeptides
  • Protease Inhibitor Specificity Index
  • Protease Inhibitors
  • R to