ChemicalBook > CAS DataBase List > 4'-Methylpropiophenone
4'-Methylpropiophenone
- Product Name
- 4'-Methylpropiophenone
- CAS No.
- 5337-93-9
- Chemical Name
- 4'-Methylpropiophenone
- Synonyms
- 4-METHYLPROPIOPHENONE;1-(p-Tolyl)propan-1-one;ETHYL-P-TOLYLKETON;LABOTEST-BB LT00053050;4-Methylpropiophenon;P-METHYLPROPIOPHENONE;P-Methyl phenylethylketone;Ethyl 4-methylphenyl ketone;1-(4-methylphenyl)-propan-1-one;4-Methylpropiophenone wickr bettyml
- CBNumber
- CB8116040
- Molecular Formula
- C10H12O
- Formula Weight
- 148.2
- MOL File
- 5337-93-9.mol
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4'-Methylpropiophenone Property
- Melting point:
- 7.2 °C
- Boiling point:
- 238-239 °C(lit.)
- Density
- 0.993 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.528(lit.)
- Flash point:
- 229 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in chloroform and hexane.
- form
- Oil
- color
- Colourless
- Specific Gravity
- 0.99
- BRN
- 2042137
- InChI
- InChI=1S/C10H12O/c1-3-10(11)9-6-4-8(2)5-7-9/h4-7H,3H2,1-2H3
- InChIKey
- PATYHUUYADUHQS-UHFFFAOYSA-N
- SMILES
- C(C1=CC=C(C)C=C1)(=O)CC
- CAS DataBase Reference
- 5337-93-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 4'-Methylpropiophenone(5337-93-9)
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Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29143990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 517925
- Product name
- 4′-Methylpropiophenone
- Purity
- 90%, technical grade
- Packaging
- 100ml
- Price
- $81.3
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M0768
- Product name
- 4'-Methylpropiophenone
- Purity
- >95.0%(GC)
- Packaging
- 25mL
- Price
- $34
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M0768
- Product name
- 4'-Methylpropiophenone
- Purity
- >95.0%(GC)
- Packaging
- 500mL
- Price
- $246
- Updated
- 2025/07/31
Oakwood
- Product number
- 216656
- Product name
- 1-(p-Tolyl)propan-1-one
- Purity
- 98%
- Packaging
- 25g
- Price
- $10
- Updated
- 2021/12/16
AK Scientific
- Product number
- J53678
- Product name
- 4'-Methylpropiophenone
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
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4'-Methylpropiophenone Chemical Properties,Usage,Production
Chemical Properties
clear light yellow liquid
Uses
4'-methylpropiophenone has been reported to be used in the synthesis of pharmaceutical compounds such as tolperisone and other muscle relaxants. The substance is also a starting material in the synthesis of 4-methylmethcathinone (mephedrone). Mephedrone has been encountered as a ‘legal high’ and on the illicit drug market masquerading as cocaine (in powder form), MDMA (in tablet form) and as an adulterant. According to the 2016 European Drugs Market Report produced by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), mephedrone has created a specific demand and carved its own distinct market share.
Uses
4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions.
Application
4′-Methylpropiophenone can be used as a building block to synthesize:
N-(4-Chlorophenyl)-N′-[1-(4-methylphenyl)propyl]urea as a potential CRAC channel inhibitor.
Mono and trinuclear cobaloxime/organocobaloxime complexes, which are used as efficient catalysts for the synthesis of cyclic carbonates.
Tolperisone (TOL) via acid-catalyzed reaction with piperidine hydrochloride and 1,2-dioxolane.
Definition
ChEBI: 4-methylpropiophenone is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone.
Synthesis
4'-Methylpropiophenone can be synthesized through various methods. One common approach involves the reaction of propiophenone with methylmagnesium bromide or methyl lithium in the presence of a catalyst. Another method utilizes Friedel-Crafts acylation, where propiophenone is acylated with methyl chloride or methyl bromide using a Lewis acid catalyst. These methods allow for the controlled introduction of the methyl group onto the phenyl ring.
4'-Methylpropiophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4'-Methylpropiophenone manufacturers
Jinan Million Pharmaceutical Co., Ltd
- Product
- 4'-Methylpropiophenone 5337-93-9
- Price
- US $1.00/box
- Min. Order
- 1box
- Purity
- 99.2
- Supply Ability
- 20tons
- Release date
- 2025-11-04
Hebei Dangtong Import and export Co LTD
- Product
- 4'-Methylpropiophenone 5337-93-9
- Price
- US $30.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 300tons
- Release date
- 2025-11-03
RongNa Biotechnology Co.,Ltd
- Product
- 1-(4-methylphenyl)-propan-1-one 5337-93-9
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2025-05-16
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