Reactions
ChemicalBook > CAS DataBase List > (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE

Reactions
Product Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
CAS No.
442905-33-1
Chemical Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
Synonyms
(R)-Xyl-P-Phos;(S)-XYLYL-P-PHOS;(R)-XYLYL-P-PHOS;CTH-(S)-XYLYL-P-PHOS;CTH-(R)-XYLYL-P-PHOS;min.cth-(r)-xylyl-p-phos;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&;(R)-(+)-2,2'',6,6''-Tetramethoxy-4,4''-bis(di(3,5-xylyl)phosphi;(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
CBNumber
CB8116202
Molecular Formula
C46H50N2O4P2
Formula Weight
756.85
MOL File
442905-33-1.mol
More
Less

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Property

Melting point:
190-194°C
Boiling point:
791.1±60.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.76±0.38(Predicted)
form 
Powder
color 
white to pale yellow
optical activity
[α]20/D +125°, c = 1 in chloroform
Water Solubility 
Sparingly soluble in water.
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
676004
Product name
(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine
Purity
97%
Packaging
100mg
Price
$101
Updated
2024/03/01
Sigma-Aldrich
Product number
676004
Product name
(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(di(3,5-xylyl)phosphino)-3,3′-bipyridine
Purity
97%
Packaging
500mg
Price
$408
Updated
2023/06/20
Alfa Aesar
Product number
044613
Product name
(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine
Packaging
0.1g
Price
$73.65
Updated
2024/03/01
Alfa Aesar
Product number
044613
Product name
(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine
Packaging
0.5g
Price
$243.65
Updated
2024/03/01
Strem Chemicals
Product number
15-5210
Product name
(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine, min. 97% CTH-(R)-Xylyl-P-PHOS
Packaging
100mg
Price
$74
Updated
2024/03/01
More
Less

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties,Usage,Production

Reactions

  1. Chiral ligand for ruthenium- catalyzed asymmetric hydrogenation of aromatic ketones.
  2. Chiral ligand for iridium-catalyzed asymmetric hydrogenation of quinolines.
  3. Chiral ligand for copper- catalyzed asymmetric hydrosilylation of ketones.
  4. Synthesis of new chiral 2-functionized-1,2,3,4-tetrahydroquinoline derivatives via asymmetric hydrogenation of substituted quinolines.
  5. Rhodium-biphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

Chemical Properties

White solid

Uses

(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine is used in asymmetric hydrogenation.It acts as a ligand used in the asymmetic hydrogenation of β-keto esters, 2-arylacrylates, aryl ketones , and other substrates. Other applications include it is used widely as a Catalyst, when combined with Rh, Ru and Ir precursor.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7191
Advantage
65
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
LaaJoo
Tel
021-60702684 18516024827
Email
huang.jiayi@sinocompound.com
Country
China
ProdList
2603
Advantage
58
Greenherbs Science and Technology Development Co., Ltd.
Tel
010-61136123
Fax
+86 (10) 8857-9127
Email
pub02@greenherbs.com.cn
Country
China
ProdList
4049
Advantage
58

442905-33-1, (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINERelated Search:


  • CTH-(R)-XYLYL-P-PHOS
  • CTH-(S)-XYLYL-P-PHOS
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE
  • (R)-XYLYL-P-PHOS
  • (S)-XYLYL-P-PHOS
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS&
  • min.cth-(r)-xylyl-p-phos
  • (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine,min.95%CTH-(R)-Xylyl-P-Phos
  • (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(di(3,5-xylyl)phosphino)-3,3'-bipyridine Application:Asymmetric hydrogenation Store N2Ar
  • (3R)-4,4'-Bis[bis(3,5-dimethylphenyl)phosphino]-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • (R)-Xyl-P-Phos
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE,MIN.97%CTH-(R)-XYLYL-P-PHOS
  • (R)-4,4'-Bis(bis(3,5-dimethylphenyl)phosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • 3,3'-Bipyridine, 4,4'-bis[bis(3,5-dimethylphenyl)phosphino]-2,2',6,6'-tetramethoxy-, (3R)-
  • (R)-(+)-2,2'',6,6''-Tetramethoxy-4,4''-bis(di(3,5-xylyl)phosphi
  • (R)-4,4'-Bis(bis(3,5-dimethylphenyl)phosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • 442905-33-1
  • Hydrogenation
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents