Lavoltidine
- Product Name
- Lavoltidine
- CAS No.
- 76956-02-0
- Chemical Name
- Lavoltidine
- Synonyms
- Loxtidina;loxtidine;AH-234844;Lavoltidine;Lavoltidina;Lavoltidinum;Lavoltidine [inn:ban];Lavoltidinum [inn-latin];Lavoltidina [inn-spanish];86160-82-9 (Hemisuccinate[1:1])
- CBNumber
- CB81179004
- Molecular Formula
- C19H29N5O2
- Formula Weight
- 359.471
- MOL File
- 76956-02-0.mol
N-Bromosuccinimide Price
- Product number
- API0011760
- Product name
- LAVOLTIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.51
- Updated
- 2021/12/16
Lavoltidine Chemical Properties,Usage,Production
Uses
Anti-ulcerative (histamine H2-receptor block er).
Definition
ChEBI: Loxtidine is a triazole that consists of 1,2,4-triazole bearing a methyl substituent at position 1, a hydroxymethyl substituent at position 3 and a {3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}amino group at position 5. A highly potent and selective H2-receptor antagonist. It has a role as a H2-receptor antagonist. It is a member of triazoles, a member of piperidines, an aromatic ether and a primary alcohol.
in vivo
Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1].
Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1].
| Animal Model: | Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1] |
| Dosage: | 0.5 g/L |
| Administration: | Orally (drinking water); changed weekly; for 3 months |
| Result: | Showed partial suppression of both gastric acid secretion and progression to neoplasia. |
IC 50
H2 Receptor
Lavoltidine Preparation Products And Raw materials
Raw materials
Preparation Products
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