Quinagolide
- Product Name
- Quinagolide
- CAS No.
- 87056-78-8
- Chemical Name
- Quinagolide
- Synonyms
- D07217;Norprolac;CV-205-502;Quinagolide;Quinagolide Free Base;Quinagolide (inn/ban);Quinagolide USP/EP/BP;3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline;(3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline;Sulfamide, N,N-diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]-, rel-
- CBNumber
- CB81179635
- Molecular Formula
- C20H33N3O3S
- Formula Weight
- 395.56
- MOL File
- 87056-78-8.mol
Quinagolide Property
- Melting point:
- 122.5-124°
- Boiling point:
- 539.1±60.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- pka
- 10.31±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- API0005294
- Product name
- QUINAGOLIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.04
- Updated
- 2021/12/16
Quinagolide Chemical Properties,Usage,Production
Uses
Quinagolide (CV205-502) is a non-ergot dopamine D(2) receptor agonist that promotes dopamine activity. Quinagolide has shown effectiveness in modulating endocrine function, particularly in inhibiting disorders associated with dopamine deficiency. Quinagolide is used to suppress hyperprolactinemia and corresponding clinical symptoms, showing good efficacy. Quinagolide's biological activity enables its use as an important research compound in drug isolation and analysis[1].
Definition
ChEBI: Quinagolide is an organonitrogen heterocyclic compound and an organic heterotricyclic compound.
Clinical Use
Hyperprolactinaemia
Metabolism
Quinagolide is extensively metabolised. Quinagolide and its N-desethyl analogue are the biologically active but minor components. Their inactive sulphate or glucuronide conjugates represent the major circulating metabolites. Studies performed with 3 H-labelled quinagolide revealed that more than 95% of the drug is excreted as metabolites. About equal amounts of total radioactivity are found in faeces and urine.
References
[1] Chiral Separations by Host-Guest Complexation with Cyclodextrin and Crown Ether in Capillary Zone Electrophoresis
Quinagolide Preparation Products And Raw materials
Raw materials
Preparation Products
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