Methyl 3-methoxyacrylate
- Product Name
- Methyl 3-methoxyacrylate
- CAS No.
- 34846-90-7
- Chemical Name
- Methyl 3-methoxyacrylate
- Synonyms
- METHYL TRANS-3-METHOXYACRYLATE;MAME;3-METHOXYACRYLIC ACID METHYL ESTER;3-methoxyacrylate;Brivudine Impurity 8;trans-3-methoxyacryL;Ceftibuten intermediate;Methyle3-methoxyacrylate;METHYL 3-METHOXYACRYLATE;3-Methoxy Methyl acrylate
- CBNumber
- CB8119627
- Molecular Formula
- C5H8O3
- Formula Weight
- 116.12
- MOL File
- 34846-90-7.mol
Methyl 3-methoxyacrylate Property
- Melting point:
- 3-4°C
- Boiling point:
- 56 °C18 mm Hg(lit.)
- Density
- 1.08 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.451(lit.)
- Flash point:
- 145 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Water Solubility
- Soluble in water
- form
- Liquid
- color
- Clear colorless
- InChI
- InChI=1S/C5H8O3/c1-7-4-3-5(6)8-2/h3-4H,1-2H3
- InChIKey
- AUTCCPQKLPMHDN-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C=COC
- CAS DataBase Reference
- 34846-90-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 43-36/37/38
- Safety Statements
- 24-37-37/39-26
- RIDADR
- 3334
- WGK Germany
- 1
- HS Code
- 29189900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M0995
- Product name
- Methyl 3-Methoxyacrylate
- Purity
- >95.0%(GC)
- Packaging
- 25mL
- Price
- $27
- Updated
- 2025/07/31
- Product number
- M0995
- Product name
- Methyl 3-Methoxyacrylate
- Purity
- >95.0%(GC)
- Packaging
- 500mL
- Price
- $205
- Updated
- 2025/07/31
- Product number
- M338608
- Product name
- Methyl 3-Methoxyacrylate
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P000331649
- Product name
- Methyl 3-methoxyacrylate
- Purity
- 98%
- Packaging
- 500g
- Price
- $177
- Updated
- 2021/12/16
- Product number
- CHM0010607
- Product name
- 3-METHOXYACRYLIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 100ML
- Price
- $2364.63
- Updated
- 2021/12/16
Methyl 3-methoxyacrylate Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS LIQUID
Uses
Methyl trans-3-methoxyacrylate is a natural β-?methoxyacrylate which inhibits mitochondrial respiration and exhibits fungicidal activity.
Synthesis Reference(s)
The Journal of Organic Chemistry, 45, p. 48, 1980 DOI: 10.1021/jo01289a012
Tetrahedron Letters, 24, p. 5209, 1983 DOI: 10.1016/S0040-4039(00)88398-7
Synthesis
7424-91-1
34846-90-7
The composition of the raw materials of this embodiment: 560 g of methyl acrylate, 716 g of methanol, 2.24 g of cobalt oxide, 8.96 g of indium oxide, and 17.6 g of concentrated sulfuric acid; method of preparation: methyl acrylate, methanol, and a synthesis catalyst (cobalt oxide and indium oxide) were added into a reactor, and the temperature of the reaction solution was maintained at 50 °C with sufficient stirring. Nitrogen and oxygen were charged into the reactor, and the partial pressure of nitrogen and oxygen was controlled to be 0.4 MPa to start the reaction. The reaction lasted for 16 hours. The reaction was judged to be complete when the content of methyl acrylate in the reaction solution decreased to 3%, followed by the addition of etherified reaction product. The catalyst was recovered by filtration, and petroleum ether was added to the filtrate, which was homogeneously stirred and left to stratify. The upper layer was petroleum ether layer, and the petroleum ether was recovered by distillation at atmospheric pressure to obtain the intermediate 3,3-dimethoxypropanoic acid methyl ester 703 g. Methanol and methyl acrylate were recovered from the lower aqueous phase. Methyl 3,3-dimethoxypropionate was transferred to a cracking kettle and 17.6 g of concentrated sulfuric acid was slowly added and the temperature was raised to 190 °C for 20 h of cracking reaction. All the cracking products were collected to obtain 430 g of crude methyl 3-methoxyacrylate (MAME). The crude MAME was placed in a distillation vessel and the product was purified by vacuum distillation, resulting in 478 g of the target product, methyl 3-methoxyacrylate. In this embodiment, the yield based on methyl acrylate was 82.4% and the purity of the product was 95.8%.
References
[1] Patent: WO2009/56293, 2009, A1. Location in patent: Page/Page column 8-9
[2] Patent: CN105418421, 2016, A. Location in patent: Paragraph 0020; 0023
[3] Patent: WO2009/56293, 2009, A1. Location in patent: Page/Page column 8
[4] Patent: WO2009/56293, 2009, A1. Location in patent: Page/Page column 8
[5] Patent: WO2009/56293, 2009, A1. Location in patent: Page/Page column 8
Methyl 3-methoxyacrylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 3-methoxyacrylate manufacturers
- Product
- Methyl 3-methoxyacrylate 34846-90-7
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-11-29
- Product
- Methyl 3-methoxyacrylate 34846-90-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2025-04-15
- Product
- Methyl 3-methoxyacrylate 34846-90-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-17