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Glufosinate-P

Product Name
Glufosinate-P
CAS No.
35597-44-5
Chemical Name
Glufosinate-P
Synonyms
L-Glufosinate;L-Glufosinate ammonium;L-Phosphinothricin;L-Glufosite;Glufosinate-P;Phosphinothricine;(S)-Phosphinothricin;Glufosinate Impurity 5;(S)-2-Amino-4-(hydroxymethylphosphinyl)butyric acid;(S)-4-[Hydroxy(methyl)phosphinyl]-2-aminobutyric acid
CBNumber
CB81212354
Molecular Formula
C5H12NO4P
Formula Weight
181.13
MOL File
35597-44-5.mol
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Glufosinate-P Property

Melting point:
209-210 °C
Boiling point:
519.1±45.0 °C(Predicted)
alpha 
D25 +13.4° (c = 1 in water)
Density 
1.378±0.06 g/cm3(Predicted)
pka
2.22±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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Glufosinate-P Chemical Properties,Usage,Production

Chemical Properties

A 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid that has S configuration at position 2. A glutamine synthetase inhibitor, it is used (generally as the corresponding ammonium or sodium salts, known as glufosinate-P-ammonium and glufosinate-P-sodium, respectively) as a herbicide to control annual weeds and grasses.

Definition

ChEBI: Glufosinate-P is a 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid that has S configuration at position 2. A glutamine synthetase inhibitor, it is used (generally as the corresponding ammonium or sodium salts, known as glufosinate-P-ammonium and glufosinate-P-sodium, respectively) as a herbicide to control annual weeds and grasses. It has a role as a herbicide, an EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor and an agrochemical. It is an enantiomer of a (2R)-glufosinate. It is a tautomer of a glufosinate-P zwitterion.

Biological Activity

Through oxidative stress C. elegans, racemic glufosinate-ammonium l-glufosinate-ammonium (Glufosinate-P) both mediated developmental toxicity (shortened developmental cycle, reduced body length width, promoted aging and decreased longevity), neurotoxicity (inhibited head swinging, body bending frequency acetylcholinesterase [AchE] activity) reproductive toxicity (significant reductions in number eggs offspring in vivo induced apoptosis gonadal cells). The degradation rate of L-glufosinate-ammonium was faster than that of D-glufosinate-ammonium. Based on MDA content, protein content, and antioxidant enzyme (SOD CAT) activity, Meng et al. found that L-glufosinate-ammonium could cause more severe oxidative damage than rac-glufosinate-ammonium[1-2].

References

[1] Xu Zhao . “Comparison of the chronic and multigenerational toxicity of racemic glufosinate and l-glufosinate to Caenorhabditis elegans at environmental concentrations.” Chemosphere 316 (2023): Article 137863.
[2] Tianyou Feng. “Comparative analysis of toxicity and metabolomic profiling of rac-glufosinate and L-glufosinate in zebrafish.” Aquatic Toxicology 261 (2023): Article 106618.

Glufosinate-P Preparation Products And Raw materials

Raw materials

Preparation Products

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Glufosinate-P Suppliers

Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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Shanghai Kewel Chemical Co., Ltd.
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BOC Sciences
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Hefei TNJ Chemical Industry Co.,Ltd.
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35597-44-5, Glufosinate-PRelated Search:


  • Butanoic acid, 2-amino-4-(hydroxymethylphosphinyl)-, (2S)-
  • (S)-2-Amino-4-(hydroxymethylphosphinyl)butyric acid
  • (S)-4-[Hydroxy(methyl)phosphinyl]-2-aminobutyric acid
  • (S)-Phosphinothricin
  • L-Phosphinothricin
  • Phosphinothricine
  • L-Glufosinate
  • Glufosinate Impurity 5
  • L-Glufosinate ammonium
  • L-PHOSPHINOTHRICINQ: What is L-PHOSPHINOTHRICIN Q: What is the CAS Number of L-PHOSPHINOTHRICIN
  • (2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
  • Glufosinate-P
  • L-Glufosite
  • 35597-44-5