ISOXATHION
- Product Name
- ISOXATHION
- CAS No.
- 18854-01-8
- Chemical Name
- ISOXATHION
- Synonyms
- e-48;si-6711;KARPHOS;HSDB6692;HSDB 6692;HSDB-6692;ISOXATHION;Isoxathion 0.1;ISOXATHION STANDARD;Propargite Impurity 8
- CBNumber
- CB8122146
- Molecular Formula
- C13H16NO4PS
- Formula Weight
- 313.31
- MOL File
- 18854-01-8.mol
ISOXATHION Property
- Melting point:
- <25℃
- Boiling point:
- 160°C (rough estimate)
- Density
- 1.48 g/ml
- vapor pressure
- <1.3 x 10-4 Pa (25 °C)
- storage temp.
- 0-6°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- Water Solubility
- 1.9 mg l-1 (25 °C)
- pka
- -6.17±0.28(Predicted)
- form
- liquid
- color
- Colourless to Pale Yellow
- Specific Gravity
- 1.48
- BRN
- 1222135
- EPA Substance Registry System
- Isoxathion (18854-01-8)
Safety
- Hazard Codes
- T,N
- Risk Statements
- 24/25-50/53
- Safety Statements
- 28-36/37-45-60-61
- RIDADR
- 3018
- WGK Germany
- 3
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Hazardous Substances Data
- 18854-01-8(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 76529
- Product name
- Isoxathion
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $245
- Updated
- 2022/05/15
- Product number
- I917690
- Product name
- Isoxathion
- Packaging
- 10mg
- Price
- $720
- Updated
- 2021/12/16
- Product number
- PST0000383
- Product name
- ISOXATHION
- Purity
- 98.00%
- Packaging
- 50ML
- Price
- $2695
- Updated
- 2021/12/16
- Product number
- CDX-I0049-M500
- Product name
- Isoxathion
- Purity
- ≥98%(HPLC)
- Packaging
- 500mg
- Price
- $565
- Updated
- 2021/12/16
- Product number
- CDX-I0049-M100
- Product name
- Isoxathion
- Purity
- ≥98%(HPLC)
- Packaging
- 100mg
- Price
- $141
- Updated
- 2021/12/16
ISOXATHION Chemical Properties,Usage,Production
Description
Isoxathion is a pale yellow liquid, bp 160 ?C/0.15 mm Hg, vp <0.133mPa (25 ?C). Solubility in water is 1.9 mg/L (25 ?C). It is readily soluble in most organic solvents. Log Kow = 3.88. It is unstable to alkali.
Uses
Isoxathion is used to control sucking pests, leaf miners and some chewing pests in a variety of fruit, vegetables and ornamental plants.
Uses
Isoxathion is used as a pesticide.
Definition
ChEBI: An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group is replaced by a 5-phenyl-1,2-oxazol-3-yl group.
Metabolic pathway
The principal route of isoxathion metabolism in soil, plants and mammals is by hydrolysis, probably via the oxon to 3-hydroxy-5-phenylisoxazole which is rapidly conjugated in both plants and rats. In soils, and to a lesser extent in plants and mammals, further metabolism of 3-hydroxy- 5-phenylisoxazole proceeds via opening of the isoxazole ring to give various metabolites of which benzoic acid is one of the more important. De-ethylation of the phosphate moiety has not been observed.
Metabolism
The principal degradation route of isoxathion in animals, plants, and soil is cleavage of P?O-isoxazole through oxidative desulfuration to the oxon followed by hydrolysis to 3-hydroxy-5-phenylisoxazole, which is conjugated in both plants and rats.
Toxicity evaluation
The acute oral LD50 for rats is 112 mg/kg. NOEL (2 yr) for rats is 1.2 mg/kg b.w. DT50 in soil is 9–40 d.
Degradation
Isoxathion is unstable to alkalis (PM). The hydrolysis product, 3-hydroxy- 5-phenylisoxazole (2), yielded 5-phenyl-3H-oxazolin-2-one (3) as the major photoproduct via a photolytic rearrangement (Nakagawa et al.,1974).
ISOXATHION Preparation Products And Raw materials
Raw materials
Preparation Products
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