2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE
- Product Name
- 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE
- CAS No.
- 936-16-3
- Chemical Name
- 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE
- Synonyms
- 1,2-benzoisothiazoline 1,1-dioxide;2,3-dihydro-1,2-benzothiazole 1,1-dioxide;2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE;2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide;2,3-dihydro-1,2-benzisothiazole 1,1-dioxide;1,2-Benzisothiazole, 2,3-dihydro-, 1,1-dioxide;2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
- CBNumber
- CB8123446
- Molecular Formula
- C7H7NO2S
- Formula Weight
- 169.2
- MOL File
- 936-16-3.mol
2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Property
- Melting point:
- 105-107 °C(Solv: water (7732-18-5))
- Boiling point:
- 325.8±45.0 °C(Predicted)
- Density
- 1.396±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 11.21±0.20(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B204043
- Product name
- 2,3-Dihydro-1,2-benzisothiazole1,1-Dioxide
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 0680BA
- Product name
- 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
- Packaging
- 100mg
- Price
- $176
- Updated
- 2021/12/16
- Product number
- 0680BA
- Product name
- 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
- Packaging
- 250mg
- Price
- $208
- Updated
- 2021/12/16
- Product number
- OR912878
- Product name
- 2,3-Dihydro-1,1-dioxo-1,2-benzisothiazole
- Purity
- 95%
- Packaging
- 250mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 0680BA
- Product name
- 2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
- Packaging
- 1g
- Price
- $521
- Updated
- 2021/12/16
2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Chemical Properties,Usage,Production
Synthesis
81-07-2
936-16-3
Step 1. Saccharin (10.0 g, 54.6 mmol) was slowly added to a 300 mL THF solution of LiAlH4 (2.24 g, 59.0 mmol) at 0 °C. The reaction mixture was stirred at 15 °C for 3 h in an inert atmosphere. Upon completion of the reaction, EtOAc (100 mL) was slowly added followed by 10% H2SO4 (100 mL). The organic layer was separated and washed with 100 mL of 5% sodium carbonate solution, dried over anhydrous sodium sulfate, filtered and concentrated to afford 1,2-dihydro-1,1-dioxo-1,2-benzisothiazole (4.4 g, 97%).
References
[1] Patent: WO2018/49324, 2018, A1. Location in patent: Page/Page column 25
[2] Organic Letters, 2014, vol. 16, # 6, p. 1550 - 1553
[3] Patent: WO2017/21805, 2017, A1. Location in patent: Page/Page column 174
[4] Patent: US2013/303524, 2013, A1. Location in patent: Paragraph 0268-0269
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 19, p. 8868 - 8878
2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE Suppliers
- Tel
- --
- Fax
- --
- interchim@interchim.com
- Country
- France
- ProdList
- 6302
- Advantage
- 76
View Lastest Price from 2,3-DIHYDRO-1,1-DIOXO-1,2-BENZISOTHIAZOLE manufacturers
- Product
- 2,3-dihydro-1,2-benzothiazole 1,1-dioxide 936-16-3
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2019-12-21