HYDROQUINIDINE

Product Name: HYDROQUINIDINE
CAS No.: 1435-55-8
Chemical Name: HYDROQUINIDINE
Synonyms: DHQD;DIHYDROQUINIDINE;Dihydroquinine;aluminum triacetate;Hydroxyquinidine;Dihydroquinidine,99%d.e.;(9s)-10,11-dihydro-6’-methoxycinchonan-9-ol;(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol;HYDROQUINIDINE;Hydroqninidine
CBNumber: CB8127464
Molecular Formula: C20H26N2O2
Formula Weight: 326.43
MOL File: 1435-55-8.mol

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HYDROQUINIDINE Property

Melting point:: 169-170 °C(lit.)
alpha: 226 º (C=2 IN ETOH)
Boiling point:: 464.47°C (rough estimate)
Density: 1.1117 (rough estimate)
refractive index: 1.6800 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: chloroform: 0.1 g/mL, clear
form: A crystalline solid
pka: 12.80±0.20(Predicted)
color: White to off-white
optical activity: [α]25/D +226°, c = 2 in ethanol
Merck: 13,4831
BRN: 91441
InChIKey: LJOQGZACKSYWCH-LHFMAAMQSA-N
CAS DataBase Reference: 1435-55-8(CAS DataBase Reference)
NIST Chemistry Reference: Hydroquinidine(1435-55-8)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36/37-36
RIDADR: 1544
WGK Germany: 3
RTECS: MX3016000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80967
Product name: (+)-Dihydroquinidine
Purity: phyproof? Reference Substance
Packaging: 100MG
Price: $262
Updated: 2024/03/01

Sigma-Aldrich

Product number: 359343
Product name: Hydroquinidine
Purity: 95%
Packaging: 5g
Price: $54.1
Updated: 2024/03/01

Cayman Chemical

Product number: 22295
Product name: Hydroquinidine
Purity: ≥98%
Packaging: 1g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22295
Product name: Hydroquinidine
Purity: ≥98%
Packaging: 5g
Price: $100
Updated: 2024/03/01

ChemScene

Product number: CS-4491
Product name: Hydroquinidine
Purity: 99.54%
Packaging: 25g
Price: $145
Updated: 2021/12/16

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HYDROQUINIDINE Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

antiarrhythmic, antimalarial

Purification Methods

It is slightly soluble in Et2O and H2O but readily soluble in hot EtOH. [Heidelberger & Jacobs J Am Chem Soc 41 826 1919, King J Chem Soc 523 1946.] The hydrochloride has m 273-274o, [] 26D +184o (c 1.3, MeOH) and is very soluble in MeOH and CHCl3, but less soluble in H2O, EtOH and still less soluble in dry Me2CO. [Kyker & Lewis J Biol Chem 157 707 1945, Emde Helv Chim Acta 15 557 1932, Beilstein 23/13 V 340.]

HYDROQUINIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

(DHQD)2PHAL HYDROQUINIDINE (ANTHRAQUINONE-1,4-DIYL) DIETHER HYDROQUININE (ANTHRAQUINONE-1 4-DIYL) (DHQD)2PYR

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HYDROQUINIDINE Suppliers

China 188 Europe 1 Germany 1 India 4 Slovakia 1 Switzerland 1 United Kingdom 4 United States 24 Global 224

BOC Sciences

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View Lastest Price from HYDROQUINIDINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dihydroquinidine 1435-55-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dihydroquinidine 1435-55-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Pharmahands (Taizhou) Co., Ltd.

Product: HYDROQUINIDINE 1435-55-8
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg/month
Release date: 2020-11-09

1435-55-8, HYDROQUINIDINERelated Search:

HYDROQUININE 6-Methoxyquinoline Quinidine Quinine o-(9-phenanthryl)hydroquinidine O-(4-CHLOROBENZOYL)HYDROQUINIDINE,HYDROQUINIDINE 4-CHLOROBENZOATE,O-(4-Chlorobenzoyl)hydroquinidine, Dihydroquinidine 4-chlorobenzoate hydroquinidine,monohydrochlorid HYDROQUINIDINE (R)-(+)-1-(4-PYRIDYL)ETHANOL HYDROQUINIDINE 1,4-PHTHALAZINEDIYL DIETHER HYDROQUINIDINE 2,5-DIPHENYL-4,6-PYRIMIDINEDIYL DIETHER (2R,4S,5R)-2-Hydroxymethyl-5-ethylquinuclidine 4-HEPTYLPYRIDINE HYDROCINCHONINE HYDROQUINIDINE (ANTHRAQUINONE-1,4-DIYL) DIETHER hydroquinidine gluconate HYDROQUINIDINE 9-PHENANTHRYL ETHER HYDROQUINIDINE 4-METHYL-2-QUINOLYL ETHER

(1S)-((2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-Methoxyquinolin-4-yl)Methanol

aluminum triacetate

Dihydroquinidine,99%d.e.

(S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

Quinine Sulphate Impurity 1

(9s)-10,11-dihydro-6’-methoxycinchonan-9-ol

(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol

10,11-Dihydroquinidine

11-dihydro-6’-methoxy-1(9s)-cinchonan-9-o

6'-Methoxy-10,11-dihydrocinchonan-9-ol

Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-

Hydroconchinine

Hydroconquinine

DIHYDROQUINIDINE

HYDROQUINIDINE

2-Hydroquinidine

{5-ethyl-1-azabicyclo[2.2.2]octan-2-yl}(6-Methoxyquinolin-4-yl)Methanol

Hydroquinidine (base and/or unspecified salts)

(1β,4β,7R,αS)-α-(6-Methoxy-4-quinolyl)-5β-ethyl-1-azabicyclo[2.2.2]octane-7-methanol

Hydroqninidine

(5-Ethyl-1-azabicyclo[2.2.2]octan-7-yl)-(6-methoxyquinolin-4-yl)methanol

(8a,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol

hydroquinidine anhydrous

Hydroxyquinidine

Dihydroquinine

Hydroquinidine,Dihydroquinidine

(4beta,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol

(8xi,9S)-6'-methoxy-10,11-dihydrocinchonan-9-ol

(9S)-6'-methoxy-10,11-dihydrocinchonan-9-ol

DHQD

DHQD Dihydroquinidine Hydroquinidine 6'-methoxy-10,11-dihydrocinchonan-9-ol (8xi,9S)-6'-methoxy-10,11-dihydrocinchonan-9-ol (9S)-6'-methoxy-10,11-dihydrocinchonan-9-ol (4beta,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol

Quinidine EP Impurity C

HYDROQUINIDINE USP/EP/BP

(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol

(+)-Hydroquinidine

Hydroquinidine (6CI, 7CI, 8CI)

(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol (dihydroquinine)

(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol (dihydroquinidine)

Quinidine impurity 1

Quinidine Impurity 3 (Quinidine EP Impurity C)

(+)-Dihydroquinidine-RM

1435-55-8

Asymmetric Synthesis

Chiral Catalysts, Ligands, and Reagents

Cinchona Alkaloids

Privileged Ligands

Inhibitors