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Research Grade Lifastuzumab(DHB65401)

Product Name
Research Grade Lifastuzumab(DHB65401)
CAS No.
1615697-16-9
Chemical Name
Research Grade Lifastuzumab(DHB65401)
Synonyms
Research Grade Lifastuzumab;Research Grade Lifastuzumab(DHB65401)
CBNumber
CB812784022
Formula Weight
0
MOL File
Mol file
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Research Grade Lifastuzumab(DHB65401) Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Research Grade Lifastuzumab(DHB65401) Chemical Properties,Usage,Production

Uses

Lifastuzumab is a humanized anti-NaPi2b monoclonal antibody (IgG1 type). Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) through ADC Linker to form an antibody-drug conjugate (ADC) lifastuzumab vedotin (DNIB0600A) with anticancer activity[1].

References

[1] Banerjee S, et al. Anti-NaPi2b antibody-drug conjugate lifastuzumab vedotin (DNIB0600A) compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer in a randomized, open-label, phase II study. Ann Oncol. 2018 Apr 1;29(4):917-923. DOI:10.1093/annonc/mdy023

Research Grade Lifastuzumab(DHB65401) Preparation Products And Raw materials

Raw materials

Preparation Products

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Research Grade Lifastuzumab(DHB65401) Suppliers

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