ChemicalBook > CAS DataBase List > 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE

Product Name
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
CAS No.
61856-99-3
Chemical Name
2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
Synonyms
EMPO;2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE;2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide
CBNumber
CB8131546
Molecular Formula
C8H13NO3
Formula Weight
171.19
MOL File
Mol file
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2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Property

Boiling point:
120 °C(Press: 0.3 Torr)
Density 
1.249 g/cm3
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
pka
1.79±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20618
Product name
EMPO
Purity
≥98%
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
20618
Product name
EMPO
Purity
≥98%
Packaging
10mg
Price
$84
Updated
2024/03/01
Cayman Chemical
Product number
20618
Product name
EMPO
Purity
≥98%
Packaging
25mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
20618
Product name
EMPO
Purity
≥98%
Packaging
50mg
Price
$299
Updated
2024/03/01
AK Scientific
Product number
3241CT
Product name
2H-Pyrrole-2-carboxylicacid,3,4-dihydro-2-methyl-,ethylester,1-oxide
Packaging
25mg
Price
$289
Updated
2021/12/16
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2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Chemical Properties,Usage,Production

Description

EMPO is a hydrophilic cyclic nitrone analog of the free radical spin trap DMPO . The EMPO-superoxide adduct (EMPO-OOH) exhibits an ESR spectrum that is similar to the DMPO-OOH spectrum. However, the EMPO-OOH adduct is about 5-8 times more stable (t1/2 = 4.8 – 8.6 min) and does not spontaneously decay to the hydroxyl adduct, making spectral interpretation less difficult.

Uses

EMPO is a free radical scavenger. EMPO is stable in phosphate buffers at physiological pH, its superoxide spin adducts are more durable and no hydroxyl adducts are produced when decaying. EMPO can be used in the study of free radicals[1].

References

[1] Olive G, et al. 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties. Free Radic Biol Med. 2000 Feb 1;28(3):403-8. DOI:10.1016/s0891-5849(99)00254-3

2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE Suppliers

CHINA 29 Switzerland 1 United States 2 Global 32
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61856-99-3, 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDERelated Search:


  • 2-ETHOXYCARBONYL-2-METHYL-3,4-DIHYDRO-2H-PYRROLE-1-OXIDE
  • EMPO
  • 2H-Pyrrole-2-carboxylic acid, 3,4-dihydro-2-methyl-, ethyl ester, 1-oxide
  • 61856-99-3