lithospermic acid B

Product Name: lithospermic acid B
CAS No.: 121521-90-2
Chemical Name: lithospermic acid B
Synonyms: Danfensuan B;Salvialic acid B;Salvianolate;alvianolic acid B;Lithospermic acid B;Salvianolic acid B-RM;Extra Cas No: 115939-25-8;Salvianolic Acid B (25 mg);Salvianolic acid B Cas 115939-25-8;lithospermic acid B|||Dan Shen Suan B
CBNumber: CB81330946
Molecular Formula: C36H30O16
Formula Weight: 718.61
MOL File: 121521-90-2.mol

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lithospermic acid B Property

Melting point:: 98-110°C
Boiling point:: 1020.3±65.0 °C(Predicted)
Density: 1.637±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: H2O: ≥5mg/mL
pka: 2.77±0.10(Predicted)
form: powder
color: white to tan
optical activity: [α]/D +95 to +115°, c = 1 in methanol
InChIKey: SNKFFCBZYFGCQN-VWUOOIFGSA-N

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: DF6492107
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 49724
Product name: Salvianolic acid B
Purity: analytical standard
Packaging: 10mg
Price: $410
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1609818
Product name: Salvianolic acid B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $365
Updated: 2024/03/01

Cayman Chemical

Product number: 9001577
Product name: Salvianolic Acid B
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 9001577
Product name: Salvianolic Acid B
Purity: ≥95%
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001559
Product name: Salvianolic acid B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001559
Price: $153
Updated: 2024/03/01

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lithospermic acid B Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. This compound always contains a significant amount of residual solvent.

Definition

ChEBI: Salvianolic acid B is a member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza It has a role as a plant metabolite, an anti-inflammatory agent, an antioxidant, a hypoglycemic agent, an osteogenesis regulator, an apoptosis inducer, a hepatoprotective agent, a neuroprotective agent, a cardioprotective agent, an autophagy inhibitor, an antidepressant and an antineoplastic agent. It is a polyphenol, a member of 1-benzofurans, an enoate ester, a dicarboxylic acid and a member of catechols.

General Description

Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.

Biochem/physiol Actions

Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease. Several mechanisms of action have been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.

target

SIRT

lithospermic acid B Preparation Products And Raw materials

Raw materials

Preparation Products

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lithospermic acid B Suppliers

Americas 1 Canada 1 China 203 Europe 1 India 3 Japan 1 United States 12 Global 222

Shanghai Aoyeah Chemical Technology Co., Ltd.

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Sinopharm Chemical Reagent Co,Ltd.

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View Lastest Price from lithospermic acid B manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Lithospermic Acid B 121521-90-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 10% 40% 50% 60%
Supply Ability: 1000 kg
Release date: 2024-04-24

Career Henan Chemical Co

Product: salvianolic acid B 121521-90-2
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

Chengdu GLP biotechnology Co Ltd

Product: Salvianolic acid B Cas 115939-25-8 121521-90-2
Price: US $1.00/mg
Min. Order: 5mg
Purity: 98%
Supply Ability: 1kg
Release date: 2019-04-15

121521-90-2, lithospermic acid BRelated Search:

PHENYLETHYL-CROTONATE Phenethyl cinnamate Salvianolic acid B FEMA 3632 (R)-3-(4-HYDROXYPHENYL)LACTIC ACID 3-(4-Hydroxyphenyl)lactate 4-vinyl-2，3-dihydrobenzofurane 2-BENZYLOXYPHENYLACETIC ACID CAPE Isopropyl ferulate magnessium lithospermate B Danshensu Phenethyl phenylacetate lithospermic acid lithospermic acid B Rosmarinic acid PHENYL ETHYL LACTATE METHYL 2-(PHENYLMETHOXY)-BENZENEACETATE

3-(1-Carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylate (2S-(2alpha,3beta(S*),4(E(S*))))-

3-Benzofurancarboxylic acid, 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) ester, (2S-(2alpha,3beta(S*),4(E(S*))))-

Salvialic acid B

Lithospermic acid B

Danfensuan B

SALVIANOLIC ACID B;LITHOSPERMIC ACID B;DANFENSUAN B

Extra Cas No: 115939-25-8

(2S,3S)-4-[(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester

Salvianolic Acid B (25 mg)

Salvianolic acid B, 98%, from Salvia miltiorrhiza

Salvianolic acid B, froM Salvia Miltiorrhiza

Salvianolic acid B Cas 115939-25-8

3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-

(R)-2-(((2S,3S)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid

(R)-2-[[(2S,3S)-4-[(E)-3-[(R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-en-1-yl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl]oxy]-3-(3,4-dihydroxyphenyl)propan

Salvianolate

alvianolic acid B

lithospermic acid B|||Dan Shen Suan B

Salvianolic acid B-RM

121521-90-2

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