lithospermic acid B
- Product Name
- lithospermic acid B
- CAS No.
- 121521-90-2
- Chemical Name
- lithospermic acid B
- Synonyms
- Danfensuan B;Salvialic acid B;Salvianolate;alvianolic acid B;Lithospermic acid B;Salvianolic acid B-RM;Extra Cas No: 115939-25-8;Salvianolic Acid B (25 mg);Salvianolic acid B Cas 115939-25-8;lithospermic acid B|||Dan Shen Suan B
- CBNumber
- CB81330946
- Molecular Formula
- C36H30O16
- Formula Weight
- 718.61
- MOL File
- 121521-90-2.mol
lithospermic acid B Property
- Melting point:
- 98-110°C
- Boiling point:
- 1020.3±65.0 °C(Predicted)
- Density
- 1.637±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: ≥5mg/mL
- pka
- 2.77±0.10(Predicted)
- form
- powder
- color
- white to tan
- optical activity
- [α]/D +95 to +115°, c = 1 in methanol
- InChIKey
- SNKFFCBZYFGCQN-VWUOOIFGSA-N
- SMILES
- O1C2=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC3=CC=C(O)C(O)=C3)=O)=C2[C@H](C(O[C@@H](C(O)=O)CC2=CC=C(O)C(O)=C2)=O)[C@H]1C1=CC=C(O)C(O)=C1
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- DF6492107
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 49724
- Product name
- Salvianolic acid B
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $410
- Updated
- 2024/03/01
- Product number
- 1609818
- Product name
- Salvianolic acid B
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $365
- Updated
- 2024/03/01
- Product number
- 9001577
- Product name
- Salvianolic Acid B
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 9001577
- Product name
- Salvianolic Acid B
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2024/03/01
- Product number
- Y0001559
- Product name
- Salvianolic acid B
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0001559
- Price
- $153
- Updated
- 2024/03/01
lithospermic acid B Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. This compound always contains a significant amount of residual solvent.
Definition
ChEBI: Salvianolic acid B is a member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza It has a role as a plant metabolite, an anti-inflammatory agent, an antioxidant, a hypoglycemic agent, an osteogenesis regulator, an apoptosis inducer, a hepatoprotective agent, a neuroprotective agent, a cardioprotective agent, an autophagy inhibitor, an antidepressant and an antineoplastic agent. It is a polyphenol, a member of 1-benzofurans, an enoate ester, a dicarboxylic acid and a member of catechols.
General Description
Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.
Biochem/physiol Actions
Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease. Several mechanisms of action have been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.
target
SIRT
lithospermic acid B Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from lithospermic acid B manufacturers
- Product
- Lithospermic Acid B 121521-90-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 10% 40% 50% 60%
- Supply Ability
- 1000 kg
- Release date
- 2024-04-24
- Product
- salvianolic acid B 121521-90-2
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ＞98%
- Supply Ability
- 20 tons
- Release date
- 2020-02-10
- Product
- Salvianolic acid B Cas 115939-25-8 121521-90-2
- Price
- US $1.00/mg
- Min. Order
- 5mg
- Purity
- 98%
- Supply Ability
- 1kg
- Release date
- 2019-04-15