lithospermic acid

Product Name: lithospermic acid
CAS No.: 28831-65-4
Chemical Name: lithospermic acid
Synonyms: Aids071478;Aids-071478;Alkaloic acid;Lithospermsaeure;lithospermic acid;Clinopodic acid H;Lithospermic acid-RM;(+)-Lithospermic acid;lithospermic acid, 10 mM in DMSO;4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
CBNumber: CB91357544
Molecular Formula: C27H22O12
Formula Weight: 538.46
MOL File: 28831-65-4.mol

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lithospermic acid Property

Melting point:: 183-188 °C
Boiling point:: 862.6±65.0 °C(Predicted)
Density: 1.642±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in methan
form: powder
pka: 2.77±0.10(Predicted)
color: White
InChIKey: UJZQBMQZMKFSRV-RGKBJLTCSA-N
SMILES: O1C2=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC3=CC=C(O)C(O)=C3)=O)=C2[C@H](C(O)=O)[C@H]1C1=CC=C(O)C(O)=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL80491
Product name: Lithospermic acid
Purity: phyproof<SUP>®</SUP> Reference Substance
Packaging: 10 mg
Price: $485
Updated: 2025/07/31

Usbiological

Product number: 300579
Product name: Lithospermic acid
Packaging: 20mg
Price: $433
Updated: 2021/12/16

ChemScene

Product number: CS-0009855
Product name: Lithospermicacid
Purity: 99.56%
Packaging: 5mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0009855
Product name: Lithospermicacid
Purity: 99.56%
Packaging: 10mg
Price: $140
Updated: 2021/12/16

AK Scientific

Product number: X1174
Product name: Lithospermicacid
Packaging: 10mg
Price: $184
Updated: 2021/12/16

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lithospermic acid Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of Salvia miltiorrhiza, Lithospermum erythrorhizon of the Boraginaceae family.

Uses

Shikoric acid has the functions of improving kidney function, preventing and treating cardiovascular diseases, and anti-oxidation.

Biological Activity

Lithospermic acid, a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, has antioxidant and hepatoprotective activities against CCl4-induced acute and in vitro liver injury.

in vivo

Lithospermic acid (50 mg/kg, po for 6 days) exhibits cardioprotective efficacy against MI/R injury in mouse models^[2].
Lithospermic acid (10-30 mg/kg, po, single dose) exhibits uric acid lowering and anti-inflammatory effects in rats hyperuricemia and gouty arthritis models^[3].

Animal Model:	C57BL/6 mouse MI/R injury models^[2]
Dosage:	50 mg/kg
Administration:	po for 6 days
Result:	Improved MI/R-induced cardiac dysfunction.

Animal Model:	Hyperuricemia and gouty arthritis model^[3]
Dosage:	10-30 mg/kg
Administration:	po, single dose
Result:	Reduced the serum uric acid and monosodium urate crystal-induced paw edema.

target

ROS | ERK | MMP(e.g.TIMP) | DNA/RNA Synthesis | Caspase | TNF-α | HIV | SOD | GPx | Xanthine oxidas | MPO | MDA

lithospermic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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lithospermic acid Suppliers

China 201 India 2 United Kingdom 1 United States 15 Global 219

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13681877033
Email: 2702713455@qq.com
Country: China
ProdList: 9997
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

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Fax: 021-55068248
Email: shyysw007@163.com
Country: China
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Advantage: 60

T&W GROUP

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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

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View Lastest Price from lithospermic acid manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Lithospermic acid 28831-65-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-02-25

Zhuozhou Wenxi import and Export Co., Ltd

Product: lithospermic acid 28831-65-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: lithospermic acid 28831-65-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

28831-65-4, lithospermic acidRelated Search:

ELEUTHEROSIDE B Ethyl acetate Shikonin CORYNOLINE griffonin Dihydroechinofuran Perilla oil (+)-CORYDALINE Przewaquinone A Pterostilbene Murexide DECURSINOL ANGELATE Shikalkin Alkannin VIOLURIC ACID MONOHYDRATE VIOLURIC ACID 2-BENZYLOXYPHENYLACETIC ACID Isopropyl ferulate

lithospermic acid

4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid

Aids071478

Aids-071478

Clinopodic acid H

(2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid

3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S,3S)-

(2S,3S)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carboxylic acid

(+)-Lithospermic acid

(2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylicaci

Lithospermsaeure

Alkaloic acid

Lithospermic acid-RM

lithospermic acid, 10 mM in DMSO

28831-65-4

C27H22O12

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract