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Shikalkin

Product Name
Shikalkin
CAS No.
54952-43-1
Chemical Name
Shikalkin
Synonyms
shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
CBNumber
CB3273506
Molecular Formula
C16H16O5
Formula Weight
288.3
MOL File
54952-43-1.mol
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Shikalkin Property

Melting point:
144-145 °C
Boiling point:
567.4±50.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
methanol: soluble1mg/mL
form 
powder or solid
pka
7.34±0.20(Predicted)
color 
red to brown
LogP
4.350 (est)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-50/53
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S7576
Product name
Shikonin
Purity
≥98% (HPLC)
Packaging
10mg
Price
$473
Updated
2024/03/01
Sigma-Aldrich
Product number
S7576
Product name
Shikonin
Purity
≥98% (HPLC)
Packaging
50mg
Price
$1620
Updated
2024/03/01
TRC
Product number
S357605
Product name
(±)-Shikonin
Packaging
5mg
Price
$85
Updated
2021/12/16
AK Scientific
Product number
0282AQ
Product name
Shikonin
Packaging
10mg
Price
$162
Updated
2021/12/16
Arctom
Product number
SY232843
Product name
(±)-Shikonin
Purity
≥98%
Packaging
10mg
Price
$74.45
Updated
2021/12/16
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Shikalkin Chemical Properties,Usage,Production

Uses

Shikonin has been used:

  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

Definition

ChEBI: C.I. Natural Red 20 is a naphthoquinone.

General Description

Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.

Biochem/physiol Actions

Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.

Shikalkin Preparation Products And Raw materials

Raw materials

Preparation Products

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Shikalkin Suppliers

Nantong Feiyu Biological Technology CO.,LTD
Tel
0513-68819626; 13813788405
Fax
0513-68669626
Email
feiyubio2@163.com
Country
China
ProdList
4821
Advantage
58
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10006
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
Country
United States
ProdList
2559
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
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View Lastest Price from Shikalkin manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Shikalkin 54952-43-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-29
Shanghai Standard Technology Co., Ltd.
Product
Shikalkin 54952-43-1
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-16

54952-43-1, ShikalkinRelated Search:


  • 5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione
  • SHIKALKIN
  • 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci)
  • Arnebin-4
  • Nsc 291845
  • shiconin
  • Shikonin (mixture of optical isomers, about 1:1)
  • 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)-
  • Shikonin >=98% (HPLC)
  • (+-)-Shikonin
  • (Rac)-Shikonin
  • 5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
  • Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin
  • 54952-43-1
  • Inhibitors
  • Coronavirus